Excited to collaborate with BMI OrganBank on their $3.5M NIH grant to advance kidney preservation technology! The Duke Ex Vivo Organ Lab, led by Andrew Barbas , will evaluate this innovation in preclinical models, paving the way for clinical trials. otc.duke.edu/news/bmi-organ…

Hot off the press! Our latest study "Transforming the logistics of liver transplantation with normothermic machine perfusion: Clinical impact versus cost" has just been published in Liver Transplantation Journal (LTxJournal). Read here; journals.lww.com/lt/abstract/99… Andrew Barbas Qimeng Gao Isaac Alderete Nihal AYKUN

Concerns have been raised that TA-NRP may damage DCD lungs. Here, we used national data and risk-adjusted models from the SRTR to show that TA-NRP is not associated with lower rates of adjusted lung utilization compared to direct recovery. Duke Ex Vivo Organ Lab Arya Pontula Sammy Halpern

Proud to co–first author this new @AmJTransplant paper. We demonstrated that AAV-PD-L1 gene therapy can reduce rejection in a rodent lung transplant model. A step toward immunomodulation through gene delivery. Qimeng Gao Nihal AYKUN Alan Rosales, PhD Duke Ex Vivo Organ Lab Duke Surgery

Article in Press! Can gene therapy help prevent rejection? AAV-mediated PD-L1 delivery during cold storage was associated with reduced acute rejection in a rat lung transplant model. amjtransplant.org/article/S1600-… Isaac Alderete Duke Ex Vivo Organ Lab Qimeng Gao Nihal AYKUN Duke Surgery

One year of working with rat lungs complete! 🐀🫁 Grateful to Dr. Matthew Hartwig for his mentorship at the Duke DEVOL Lab (Duke Ex Vivo Organ Lab) and to Duke University School of Medicine for honoring our research with the GlaxoSmithKline James B.D. Palmer, MD Memorial Scholarship Fund! 🥼🔬