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To treat OCD, Deep Brain Stimulation to the ventral capsule is effective – but the optimal target site remains unclear. In a huge collaborative effort Garance Meyer & Clemens Neudorfer set out to determine it Biological Psychiatry. A 🧵 👇👇 researchgate.net/publication/37…

We’ve all heard of place cells: neurons that form a “cognitive map” representing the structure of the outside world. But what about our own structured behaviours? We took a deep mechanistic dive, out now on bioRxiv : biorxiv.org/content/10.110… 🧵below:

nin.nl/vacancies/post…

Excited about our long-brewing paper exploring dynamics in multi-regional neural circuits in a delayed movement task. Driven by@esthersselva, Yi Liu, and including Jennifer Colonell, Nuo Li and Shaul Druckmann and others (the MAP collaboration): cell.com/cell/fulltext/… (1/7)

Want to flexibly manipulate many cortical regions, but don't know how to build a random access optogenetics system? We present Zapit: an #opensource hardware and user-friendly software system to make this technology more widely available. Our preprint: doi.org/10.1101/2024.0…

Happy to see this paper from my old PhD lab finally out! We compared the influence of sensory inputs and reward outcome across 4 regions along the cortico-hippocampal hierarchy during a multisensory object recognition task. academic.oup.com/cercor/article…

Excited to share my PhD work in Peyman Golshani 's lab designing and building low-cost miniature 2P microscopes with everyone! They cost < $10k USD (even at low production runs), are fitted with 2 on-board SiPM detectors, and are completely open-source! 1/5 biorxiv.org/content/10.110…

A GitHub flaw lets attackers upload executables that appear to be hosted on a company's official repo, such as Microsoft's—without the repo owner knowing anything about it. The following URLs, for example, make it seem like these ZIPs are present on Microsoft's source code repo:

Happy to announce that our paper on PdCO is finally out Nature Methods - check out this great tutorial by the awesome @JWietek:

Dopamine world : "Value-driven adaptations of mesolimbic dopamine release are governed by both model-based and model-free mechanisms" is the title of our latest publication spearheaded by PhD student Rhiannon Robke! eneuro.org/content/early/…

arXiv -> alphaXiv Students at Stanford have built alphaXiv, an open discussion forum for arXiv papers. alphaXiv You can post questions and comments directly on top of any arXiv paper by changing arXiv to alphaXiv in any URL!

Very proud of this important work on how thyroid status impacts the brain and behavior. Led by postdoc Dan Hochbaum who assembled quite a team urldefense.proofpoint.com/v2/url?u=https…

We are hiring! Project 1: We have a postdoc position on neural circuits through which early life risky play opportunities affect later life resilience in rats. Team effort with Heidi Lesscher Fiber photometry / Patch clamp / chemogen Please distribute. careersatumcutrecht.com/vacancies/wete…

The first piece of work from my PhD has now been uploaded to biorXiv! Short 🧵below:

This is something we are very excited about. Bart Lodder led this development project collaborating with Lin Tian, PhD lab. The technology makes lifetime photometry easy and, with the new dopamine sensor, allows measurements of phasic and tonic DA in vivo biorxiv.org/content/10.110…

If you are interested how to measure absolute neurotransmitter release or neuronal signals in vivo over long time-scales and at high speed, please check out our new pre-print, where we use FLIPR to measure phasic and tonic dopamine in freely moving mice. biorxiv.org/content/10.110…

Thrilled to share my postdoc work from Takaki Komiyama lab, showing how motor learning reshapes thalamic influence on motor cortex to enable learned movements. Hats off to our collaborators and co-authors for their incredible contributions! nature.com/articles/s4158…

Congrats to Kim Reinhold, soon to launch her own group in the Eaton Peabody Labs, on this labor of love. Basically, she shows that the visually recipient zone of the striatum mediates outcome-dependent trial to trial updates of behavior. nature.com/articles/s4158…

Review by Jaeeon Lee on the function of the indirect pathway in action selection, devaluation, and switching. nature.com/articles/s4158…

Congrats to Pingping Zhao in the lab for publishing this very useful protocol paper on GRIN lens implantation strategies journals.plos.org/plosone/articl…