🔥The 9th Round of Easy Loan, Earn $40 Reward is in progress❗️ ⏰ Promotion Period: January 15th - Feburary 15th, 2025 👉 Register now and check more details at gate.io/campaigns/358

#ThisWeekInNPP New findings from Carly Fabian Max Joffe Marianne Seney Becca Cole @WinterThompson find that parvalbumin-expressing interneurons in the PFC are more excitable in ♀️ 🐭than ♂️🐭 with sex-specific regulation by mGlu1 & mGlu5 receptors nature.com/articles/s4138…

Some photos from the inaugural Joffe lab scavenger hunt 2024

baby’s first fiber photometry signal PFC PV-INs 🫶🫶

Just received the NGA for our new NIDAnews DP1! I am thrilled we will be able to investigate new targets in SST cells for the treatment of OUD. Major thanks to the support from Colleen McClung @MoussawiKhaled Larry Zweifel, and all who helped develop and refine this proposal!

Honored to have received the official Notice of Award for my F31 NRSA application the other day! 🎉 Huge thanks to NIAAA News for supporting my work and all those who helped me through this process Max Joffe Mary Torregrossa 😊

365 party girl

so much fun + such cool science at my first Addiction GRS/GRC !!🦞🧠🥹

there is no escape

Mu and Delta Opioid Receptors Modulate Inhibition within the Prefrontal Cortex through Dissociable Cellular and Molecular Mechanisms biorxiv.org/cgi/content/sh… #biorxiv_neursci

Excited to share our first foray into opioid research! Becca Cole set out to build a comprehensive picture of opioid receptor function within PFC interneurons. Becca characterized several pronounced and contrasting effects across the major GABAergic cell types and circuits...

Presynaptic and somato-dendritic DOR functions are greatest in SST cells, while MOR's effects and putative subcellular location vary extensively across cell types. Lots of neat data in this one, including a new tool made by ⚡️GREG_CORDER⚡️ and @gsalimando to target MOR+ cells

Honored to have been selected as a finalist for the Stephen L. Phillips “Best Peer-Reviewed Publication” Award 🎉 Big thanks again to Max Joffe and Marianne Seney 😊and for Sean P Farris for coming to support! CNUP

Our lab is hiring at all levels. Currently have postings up for entry level, more senior, and postdoc positions. Please reach out if interested! careers.upmc.com/job/21068977/r… careers.upmc.com/job/21069047/r… cfopitt.taleo.net/careersection/…

DOR’s biggest fan

made it out of the lab to see Kamala Harris !!! 👑 💙 #pittsburghforharris

Excited to present some of Becca Cole's work on opioid receptor regulation of PFC transmission today! Very thorough characterization and some neat findings in a model of opioid dependence. Come find me at M217. ACNP #ACNP2024

So honored to have been 1 of the 50 recipients of this grant, which was instrumental in launching my career! In uncertain times, it’s reassuring to see Hello Bio stay committed to investing in and supporting the future. Grateful to be featured in this article—give it a read ⬇️

Incredibly grateful for my NIDAnews F31 to study DOR signaling in oxycodone dependence and withdrawal

Happy to share the latest preprint from the lab. Work examining the role of somatostatin neuropeptide transmission in the PFC in regulating associative learning underlying discrimination between salient and neutral outcomes. Led by Miguel Arenivar 🇺🇸🇲🇽🐭🧸🧪 biorxiv.org/content/10.110…