Ben Reisman MD PhD (@benjaminreisman) 's Twitter Profile
Ben Reisman MD PhD

@benjaminreisman

Onc Fellow @Hopkins_HemOnc via @OslerResidency + @VanderbiltMSTP โ€ข chemical biologist โš—๏ธ

ID: 471303604

calendar_today22-01-2012 18:28:10

1,1K Tweet

1,1K Followers

2,2K Following

Lappalainen Lab (@tuuliel_lab) 's Twitter Profile Photo

We know the importance of subtle gene dosage variation, and yet the main tool of molbio is gene KO/KD. In our new preprint, Jรบlia Domingo introduced subtle modulations of transcription factor dosage by CRISPRi/a, and quantified responses by scRNA-seq. 1/ biorxiv.org/content/10.110โ€ฆ

Ashwin Kishtagari, MD (@ashkishtagari) 's Twitter Profile Photo

A new study from Alex Bick & Ferrell Lab labs led by incredible Brett Heimlich, Pawan Bhat & Alyssa Parker! Comprehensive multi-omic profiling of 66968 single cells unveils that TET2 & DNMT3A mutations in Clonal Hematopoiesis drive distinct inflammatory pathways,

Jona Mata, MD (@jonamata26) 's Twitter Profile Photo

Proud to share our findings on Primary and Secondary Graft Failure in patients receiving AlloHSCT + PTCy as GVHD prophylaxis A very special thanks to my grand-ACS Dr. Alex Ambinder for his awesome mentorship astctjournal.org/article/S2666-โ€ฆ

Jason Sheltzer (@jsheltzer) 's Twitter Profile Photo

My lab is hiring postdocs to study aneuploidy's role in cancer! We're applying next-gen chromosome engineering approaches to uncover how gene dosage imbalances impact drug sensitivity, metabolism, immune evasion, and more. Send me your CV+cover letter if interested. Please RT!

My lab is hiring postdocs to study aneuploidy's role in cancer! We're applying next-gen chromosome engineering approaches to uncover how gene dosage imbalances impact drug sensitivity, metabolism, immune evasion, and more. 

Send me your CV+cover letter if interested. Please RT!
Pradeep Natarajan (@pnatarajanmd) 's Twitter Profile Photo

TET2 clonal hematopoiesis is enriched among individuals receiving solid organ transplantation. While this didn't predict transplant outcomes, whether it plays a role in the ultimate transplant indication requires further study aacrjournals.org/clincancerres/โ€ฆ AACR Alex Silver

Joycelyn Tan (@joycelyntsi) 's Twitter Profile Photo

Beyond excited to share my first paper from my PhD Daniel Fazakerley Lab Inst Metabolic Science-Metabolic Research Labs now out in The EMBO Journal! Special thanks to Sam from TVPLab and Dougall Norris for co-leading this project with me. We found that many cell culture models, despite living in 18% oxygen, are hypoxic! ๐Ÿงตbelow:

Brian Liau (@brian_b_liau) 's Twitter Profile Photo

Excited to share 2 preprints, together showing how mechanisms of a molecular glue & E3 ligase cancer mutations serendipitously converge to cause neomorphic protein degradation in distinct contexts. Highlights below: 1/17 #1: biorxiv.org/content/10.110โ€ฆ #2: biorxiv.org/content/10.110โ€ฆ

William Gibson (@wgibson) 's Twitter Profile Photo

TP53: - Discovered 45 years ago, most cited gene all time - No therapies - 500 million people currently living will die of TP53 mutant cancers without new therapies Our Preprint: - A general strategy for TP53 missense mutant cancers (majority) with prototype small molecules

Stephen Oh (@mpndoc) 's Twitter Profile Photo

๐Ÿ‘‹ @WashUHeme is recruiting!!!๐Ÿคฉ We are seeking physician-scientist, clinical & research faculty candidates to join our expanding #HemeDreamTeam! More details here: facultyopportunities.wustl.edu/Posting/Detailโ€ฆ facultyopportunities.wustl.edu/Posting/Detailโ€ฆ facultyopportunities.wustl.edu/Posting/Detailโ€ฆ hematology.wustl.edu @WUDeptMedicine

๐Ÿ‘‹ @WashUHeme is recruiting!!!๐Ÿคฉ 
We are seeking physician-scientist, clinical & research faculty candidates to join our expanding #HemeDreamTeam!
More details here: 
facultyopportunities.wustl.edu/Posting/Detailโ€ฆ
facultyopportunities.wustl.edu/Posting/Detailโ€ฆ
facultyopportunities.wustl.edu/Posting/Detailโ€ฆ
hematology.wustl.edu
@WUDeptMedicine
Cameron McAlpine (@cam_phd) 's Twitter Profile Photo

We are delighted to share our latest findings today in nature. We describe cardiogenic regulation of sleep after cardiac injury. โ€œMyocardial infarction augments sleep to limit cardiac inflammation and damageโ€ nature.com/articles/s4158โ€ฆ

Kelsey Fisher-Wellman, PhD (@kfw_lab) 's Twitter Profile Photo

๐Ÿ“ข New KFW Lab paper out now in Science Advances! ๐Ÿ“ข We show that AML cells resist chemotherapy by reversing the ATP synthase reactionโ€”supporting oxidative metabolism and maintaining mitochondrial membrane potential. ๐Ÿ”ฌ๐Ÿงฌ ๐Ÿ‘‰ science.org/doi/10.1126/scโ€ฆ

Vanderbilt School of Medicine Basic Sciences (@vubasicsciences) 's Twitter Profile Photo

๐Ÿงซ A practical protocol for multiplexed single-cell cytometry bridges #chemicalbiology and #cellbiologyโ€”empowering both novices and experts to explore functional assays with high-throughput precision. ๐Ÿ‘‰ doi.org/10.1016/bs.mcbโ€ฆ

๐Ÿงซ A practical protocol for multiplexed single-cell cytometry bridges #chemicalbiology and #cellbiologyโ€”empowering both novices and experts to explore functional assays with high-throughput precision. ๐Ÿ‘‰ doi.org/10.1016/bs.mcbโ€ฆ
Mark Yarchoan (@markyarchoan) 's Twitter Profile Photo

1/ Our new review is out today in Nature Reviews Cancerโ€”on why therapeutic cancer vaccines are finally gaining traction after decades of setbacks. ๐Ÿ”— rdcu.be/emkkd w/ Dr. Neeha Zaidi Dr. Elizabeth Jaffee Key takeaways below

Conor McClune (@conor_mcclune) 's Twitter Profile Photo

Today in nature we report a systematic strategy to activate & identify gene sets in plants. We identify 8 new genes from the yew tree's Taxol biosynthetic pathway, enabling us to engineer tobacco with 17- & 20-gene pathways to Taxol precursors baccatin III and dBz-deoxy-Taxol. a