🔥The 9th Round of Easy Loan, Earn $40 Reward is in progress❗️ ⏰ Promotion Period: January 15th - Feburary 15th, 2025 👉 Register now and check more details at gate.io/campaigns/358

💥BIG PAPER ALERT💥 So excited to share our latest, out now nature! Here, we uncover a spatially confined interplay between subsets of IL-1b+ macrophages and tumor cells that fuels pathogenic inflammation in pancreatic cancer (1/n) nature.com/articles/s4158…

Glad to announce that our QImmuno lab approach for TCR-pMHC specificity prediction just won silver and bronze medals in the IMMREP23 benchmark! 🥳 kaggle.com/competitions/t…

This seems a cool paper - proteins in the shapes of letters or digits !! nature.com/articles/s4158…

The Arthur and Sandra Irving Cancer Immunology Symposium Website: irvingcancerimmunologysymposium.com Hosted by Arthur and Sandra Irving symposium (from Jun 24-27, 2024 in Boston) will focus on advancing the careers of young scientists doing research in cancer immunology. Apply!!!

Three weeks left to apply to our open-rank search in AI & Infection! Come join us at UCL Division of Infection & Immunity 😀

Lightning-fast adaptive immune receptor similarity search by symmetric deletion lookup arxiv.org/abs/2403.09010 In work led by Touchchai we show how an algorithmic paradigm from spell checking can accelerate TCR clustering by orders of magnitude

OUT NOW 📢: A folate inhibitor exploits metabolic differences in Pseudomonas aeruginosa for narrow-spectrum targeting zgitai nature.com/articles/s4156…

So excited for our latest story on a tunable-spectrum antibiotic to be published. We desperately need microbiome-sparing strategies to treat P. aeruginosa. Amazing effort led by the fantastic @ConnorChain

Martina's elegant new paper defines an important and under-appreciated role for molecular interactions between CDR loops of the TCR !

How do interactions between hypervariable loops shape TCR specificity? Can patterns of sequence co-variation help us pair alpha-beta chains using techniques developed for co-evolving proteins? New work led by Martina Milighetti now out on bioRxiv! 👇

We are looking for a research fellow interested in the T cell receptor repertoire to work on some amazing cancer data sets. Check out this job at UCL: linkedin.com/jobs/view/3930…

Are you a PhD graduate in Physics, Chemistry, Earth Science, Math or Computer Science? Apply for the Max Planck-Weizmann Joint Postdoctoral Program. Includes a fully funded four-year position, split equally between these two esteemed institutions >> bit.ly/mpg_wis

We're hiring! Are you a lab scientist interested in human immunology of infectious disease, using cellular models of host-pathogen interactions and human experimental challenge, focusing on immune responses in Tuberculosis and SARS-CoV-2? Apply here: bit.ly/3yPdfO5

The latest exciting step forward in T cell receptor representation ! Yuta Nagano outperforms TCR-BERT ! arxiv.org/pdf/2406.06397

UCL Division of Infection & Immunity 👏👏👏 Fantastic, well done Paul. A great man.

New major team preprint demonstrating antibodies from #longCOVID patients are sufficient to cause pathology and behavioral symptoms when transferred to mice. Importantly, they match individual patient symptoms to potential autoantigen targets and induced mouse behaviors

Single cell analysis of the phenotype of bonemarrow T cells in myeloma reveals striking phynotypic differences from solid tumour TILS. Read our latest paper out here medrxiv.org/content/10.110…

We are delighted to announce that Professor Edith Heard has been appointed as our new director and chief executive! Edith, who is currently director-general at @EMBL, will succeed Paul Nurse in leading the Crick from the summer of 2025. 🔗 crick.ac.uk/news/2024-07-0…

For all the T cell receptor sequencers out there, the latest version of our analysis pipeline Decombinator 5.0 is live, and now on PiPy for greater ease of installtion ! Thanks to Matt Cowley for a huge amount of work ! pypi.org/project/decomb…

Can now run the whole pipeline using a single command. Much faster and more memory efficeint.