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Honored to have contributed to this awesome new study. We showed that an increase of A-to-I RNA-editing may contribute to early, initial stages of synaptic degeneration in PD. Many thanks to the Mazzulli's lab and Steven Lubbe Steven Lubbe NM Neurology doi.org/10.1016/j.neur…

Someone claimed this figure was published in Nature Reviews Genetics. I did not believe them. I was wrong.

Genetic variants identified through GWAS explain only a proportion of the heritability of Parkinson’s disease. Cisterna-Garcia et al. show that interactions between variants, known as epistasis, may account for some of the missing heritability. tinyurl.com/3wjmphee

2024 is 100% complete! Thank you all for following, and have a nice 2025!

So uh, 15 million DNA samples are now just available to the highest bidder?

Researchers at Northwestern Feinberg School of Medicine performed a genome-wide CRISPR screen & identified candidate genes that modulated #Parkinsons-associated GCase activity; They find COMMD3 is essential for lysosomal GCase activity, & variants are associated with⬆️PD risk science.org/doi/10.1126/sc…

2025 is 33% complete.

Happy to have contributed to this study in Alzheimer's Disease! "Annexin A6 membrane repair protein protects against amyloid-induced dystrophic neurites and tau phosphorylation in Alzheimer’s disease model mice" link.springer.com/article/10.100…

2025 is 50% complete.