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Don't like p-values? We're presenting a completely new interpretation in the context of clinical trials. With Andrew Gelman, Sander Greenland, guido imbens Simon Schwab and Steve Goodman. Sander Greenland Steven Goodman NEJM Evidence evidence.nejm.org/stoken/default…

Jorge Salluh, MD, PhD, joins us as the new Editor-in-Chief of the Journal. A distinguished researcher at IDOR & professor in the postgraduate program of IM at UFRJ, his top priorities for the journal will be international collaboration, diversity & inclusivity. #ICU

Did you know that it has taken some of the best mathematicians over two centuries to prove central limit theorem, first starting with de Moivre (1733), then almost a century after by Laplace who both used binomial distribution. Then it was Poisson who worked on this theorem, and

Ciência Brasileira no NEJM 👏 Vacina contra a Dengue do Butantan, num estudo randomizado controlado de fase 3. nejm.org/doi/full/10.10…

🔍 Citrate in #CRRT as a calorie source? ➡️ Sodium citrate reduces bleeding risk & extends filter life; ➡️ Significant caloric intake (200-600kcal/day); ➡️ Ignoring citrate's caloric contribution may impact nutritional planning in ICU. 🔗 bit.ly/48Svwqf #AMIB #CCS #SPCI

🌙 Melatonin & Delirium: ➡️ RCT to test if 3mg enteral melatonin reduces delirium in critically ill adults; 💊 54 received melatonin at 9 PM;  🏥 54 had standard care; ✅ Outcomes: 24-hour delirium incidence, ICU mortality... 🔗 Open access: bit.ly/4aOPALs #AMIB #SPCI

Professor Miguel Hernán of Harvard T.H. Chan School of Public Health discusses "Target Trial Emulation: A Framework for Causal Inference From Observational Data" with JAMA Statistical Editor Roger J. Lewis. ja.ma/3QupTYZ

🧵 New Special Communication examines drawing causal inferences about the effects of interventions from observational studies in medical journals and suggests a framework that might be used. ja.ma/3UxeAjL

#BMJInvestigation raises concerns about financial entanglements between US FDA chiefs and the drug and medical device companies they are responsible for regulating. Journal questions current rules governing financial holdings by FDA commissioners bmj.com/content/385/bm…

The need for better integration of clinical trials and health care delivery enterprises discussed in this first Special Communication article from #JAMASummit. Kirsten Bibbins-Domingo Alison Huang, MD, MAS Amy Abernethy Dr. Robert M. Califf Martin Landray ja.ma/4aOP4wB

NEW PAPER A mathematical perspective on imbalance corrections and the consequences on discrimination and calibration, excellently led by Marco Piccininni doi.org/10.1016/j.jbi.…

📌Atenção, até que a Lei nº 14.874/2024 entre em vigor, o funcionamento do Sistema CEP/Conep permanecerá inalterado. 🟢Informações detalhadas serão divulgadas em todos os canais de comunicação oficiais da Conep. #eticaempesquisa #cepconep #conepetica #lei14874

Introducing our editorial board- international member: Dr. Sangeeta Mehta is a #ICU MD at Sinai Health System in Toronto, Canada. She is a Professor in Medicine Dept & a Clinician Scientist in Division of Respirology & Critical Care,at University of Toronto. #CriticalCareScience

Message from our editor-in-chief Dr. Jorge Salluh MD, PhD about why you should submit your manuscript to #CriticalCareScience! #ICU #PedsICU #FoaMed #FoaCC #MedEd AMIB - Associação de Medicina Intensiva Brasileira Daniela Souza Filipe Amado, MD Vanessa S. Lanziotti Roberto Jabornisky Thiago Lisboa Otavio Ranzani @sgdrambauskas

Introducing our Editorial Board: Daniela C. Souza, MD, MSc, PhD, #PedsICU doctor at SãoPaulo University & Sírio Libanês Hospital 🇧🇷, is the current President of ILAS - Instituto Latino Americano de Sepse & a member of expert panel on Pediatric Sepsis Definitions (SCCM) & Surviving sepsis campaign. Daniela Souza

Discussion about scientific publication is still going on at #CriticalCareScience session at #CBMI2024 #ICU #PedsICU #FOAMed #FoaMcc #Livetweet

📜 Editorial about importance of publications from #LMIC 📖 importance, challenges & potential solutions for overcoming #ICU knowledge gap in LMIC criticalcarescience.org/article/closin… CCS believes in ⬆️quality research w/ Global Acess & no fee #DecolonizingGlobalHealth #FOaMed #PedsICU

Differences in relative importance of predictors of short-&-long-term mortality among #ICU patients w/cancer 🇧🇷 Retrospective cohort; ➡️ predictors of mortality post ICU admission in pts w/cancer who experienced unplanned ICU admission. criticalcarescience.org/article/differ… #FOAMed #CCS

🔬Just published ➡️ In this viewpoint,authors discuss pitfalls researchers should be aware of when conducting #ICU #research 🔹Lack of relevant research question 🔹Definition of inclusion & exclusion criteria 🔹New methods are not always the best! & more! criticalcarescience.org/article/common…

A presidente do ILAS, dra. Daniela Souza, médica da UTIP do Hospital Universitário - USP e do Hospital Sírio Libanês em São Paulo, compartilha alguns destaques imperdíveis sobre o XXI Fórum Internacional de Sepse. Dê o play e confira! Ela vai abordar o tema: Protocolo de sepse: