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Congrats Bhagirath Chaurasia! Dr. Chaurasia's study was recently accepted to the journal of Molecular Metabolism. We are proud to have you as an The University of Iowa FOEDRC member! Internal Medicine at Iowa uiowafoedrc.com/2020/12/23/foe…

Here is Bhagirath Chaurasia paper! Scott Summers U of U NUIP University of Utah College of Health @uofudmrc @DaretoDiscover Internal Medicine at Iowa @iowamed Molecular Metabolism E. Dale Abel sciencedirect.com/science/articl…

A recent pub in Molecular Metabolism from The University of Iowa FOEDRC member Bhagirath Chaurasia finds a possible therapeutic target for reducing insulin resistance in ceramides. internalmedicineiowa.org/2021/01/04/dec…

#Aging results in a blunted #thermogenic #adipocyte function, which is now linked to an accumulation of #ceramides. University of Iowa Carver College of Medicine Internal Medicine at Iowa Bhagirath Chaurasia ➡️sciencedirect.com/science/articl…

More of Bhagirath Chaurasia's work on ceramides this time in thermogenic adipocytes.

Metabolic Messenger | Ceramides are complex lipids with deleterious signaling properties Scott Summers Bhagirath Chaurasia & William Holland (University of Utah) discuss the discovery of ceramides & how these lipids could be leveraged to treat metabolic disease nature.com/articles/s4225…

Another example is NIDDK-funded research that led to a medication that helps people with type 2 diabetes lower their blood glucose while reducing their risk of cardiovascular disease. niddk.nih.gov/news/archive/2…

Hot on the heels of a pub earlier this year in Molecular Metabolism, Bhagirath Chaurasia will continue his study of #ceramides as a therapeutic target in combating #obesity & #diabetes w/an American Diabetes Association development grant. The University of Iowa FOEDRC @uiowabiomed UIowa Research internalmedicineiowa.org/2021/06/02/cha…

RockStar!

Science can be a cruel mistress. Despite the best efforts and intentions, I have seen good friends (& amazing scientists, far better than me) get ground down by despair. This is why I never take success for granted and am delighted when good people get the success they deserve.

Proud of my UW-Madison IPiB graduate students @raghav_jain1 for his first author pre-print from my lab, and Gina Wade for her first manuscript! This work explores tissue contribution to the plasma lipid pool through unbiased computational analysis.

One of my favorite parts of putting together this manuscript has been collaborating with two brilliant early investigators. Irene Ong from UW School of Medicine and Public Health and Bhagirath Chaurasia University of Iowa. Fun discussions and exciting future collaborations to follow.

Systematic assessment of lipid profiles for the discovery of tissue contributors to the circulating lipid pool in cold exposure biorxiv.org/content/10.110… Judith Simcox PhD @raghav_jain1 Gina Wade Bhagirath Chaurasia & colleagues GitHub data s/p official pub. Straight from Judy👇

Meikle et al. review the current state of clinical lipidomics and the techniques employed in lipidomic profiling, with a primary focus on mass spectrometry-based analysis — University of Melbourne Monash University Baker Institute Thomas Meikle #DiabetesAwarenessMonth jlr.org/article/S0022-…

My good friend Doug Melton — assisted by his lab, pharma companies and their investors, and volunteers like Mr Shelton — has done this amazing thing: nytimes.com/2021/11/27/hea…

Together with Ying Li and Scott Summers, in this new study we provide proof-of-principle that commercially available Cordyceps extracts inhibit ceramide biosynthesis and improves insulin resistance and hepatic steatosis. rdcu.be/cMEsT

A recent Scientific Reports pub from Bhagirath Chaurasia finds that an extract from a commercially available fungus has the ability to block a key lipid metabolite's activity and reverse diabetes, obesity, and related comorbidities in mice. internalmedicineiowa.org/2022/05/16/blo…

Check out this publication by Bhagirath Chaurasia posted earlier this month in Scientific Reports! The study demonstrates that a key lipid metabolite may be a useful targeting in preventing or even reversing diabetes and many of its comorbidities. tinyurl.com/2p8swxcc

Glad to see this finally out.

Our latest. We were surprised to uncover a role for ceramides in fuel choice of intestinal stem cells, a finding that could have implications for cancer risk. Kudos to Ying Li and Bhagirath Chaurasia for doggedly pursuing the mechanism. U of U NUIP UofU Diabetes authors.elsevier.com/a/1hoBj3mEmfkso