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World Parkinson’s Day: How Science Is Battling the Disease dlvr.it/R2fhbS

In a study led by Dr Daniel Sillence, a reader in cell biology at DMU, researchers have identified new insights into Alzheimer’s and Parkinson’s disease 💊👇 #DMUResearch #ProudToBeMore

Reader in Cell Biology, Dr Daniel Sillence's study into drugs prescribed for brain-related conditions shows promise for treating Alzheimer's and Parkinson's! 🧠💊 Read the full story 👉 ow.ly/Sauk30oswKe 👈

Great news. Congratulations 😀. So proud of William.

Drugs used for rare brain diseases could potentially also treat COVID-19, according to early research conducted by #DMUexpert Dr Daniel Sillence 💊💉🦠 He is working alongside the University of Oxford to see if existing medicines could stop the virus. #ProudToBeMoreApart #WeAreTogether

Dr Daniel Sillence, Associate Professor and Reader in Cell Biology at DMU, is working alongside the University of Oxford to investigate whether existing medicines could be repurposed to stop COVID-19 💊🔬 #WeAreTogether #ProudToBeMoreApart

A big thank you to the organisers of Lysosome FEBS Advanced Course for a fantastic week of lysosome and LSD science! Really enjoyed all the talks including from ECRs like Meenakshi Bhardwaj who gave a great talk today. I’m sad to be leaving Turkey☀️

Sphingosine kinases regulate ER contacts with late endocytic organelles and cholesterol trafficking buff.ly/3TaWXnN (#PNAS PNASNews)

Resolving subcellular pH with a quantitative fluorescent lifetime biosensor. doi.org/10.1038/s41467…

Effect of the heterogeneity of sphingomyelin on the properties of raft-like membranes buff.ly/3diQNT1 (@BBAjournals)

Cross-linking of the endolysosomal system reveals potential flotillin structures and cargo. doi.org/10.1038/s41467…

Lysosomal Targeting of β-Cyclodextrin. doi.org/10.1002/chem.2…

Species-specific differences in NPC1 protein trafficking govern therapeutic response in Niemann-Pick type C disease. doi.org/10.1172/jci.in…

Association of CSF Glucocerebrosidase Activity With the Risk of Incident Dementia in Patients With Parkinson Disease. doi.org/10.1212/WNL.00…

Fully funded UK PhD Studentship (Oct 2023): Sphingolipid targets in lysosome-related diseases using Parkinson’s patient cells and fruit flies Dr Daniel Sillence ([email protected]) and Dr Carlo Breda ([email protected]). Let your students know!

I am delighted to share that I have joined the miloseviclab as a postdoctoral researcher at the University of Oxford's Nuffield Department of Medicine.#research

2 RA posts in Cell Biology available Please share - thank you! my.corehr.com/pls/uoxrecruit…

Following the recent abandoned clinical trial for substrate reduction in GBA-PD, there is a need for new ideas and this preprint is our take on the problem. Glucosylceramide depletion disrupts endolysosomal function in GBA-linked Parkinson's fibroblasts? biorxiv.org/content/10.110…