#Today at 10am PT// 1pm ET! Register: tinyurl.com/y3u6m6b8 Test Account Tarin Bigley HIRN UF Diabetes Institute Steno Diabetes Center Aarhus @ChicagoDERC Joslin Diabetes Center UCSF School of Medicine UMassDiabetes Diabetes Research Institute Foundation @ProventionBio #WUPhysicianScientists #autoimmunity #autoantibodies #InfectiousDisease

Forty grants were funded within the department in June! Get more details 👇 @Bark_Lab Tarin Bigley Jonathan Cooper @SarahGarwoodMD Andy Glatz David Hunstad Mimi Kao Robert Potter, PhD, D(ABMM) Rebecca Same @ellen_schill Stephen Stone, MD Zachary Vesoulis news.peds.wustl.edu/funded-grants-…

Proud to share our latest work on the role of T cells in protection from classical Klebsiella pneumoniae. Wonderful effort and insights from Dr. Joseph Mackel! frontiersin.org/articles/10.33…

We are thrilled to share that so many Washington University physician-scientists have recently opened their research labs! Read all about their exciting work and help us cheer them on! wustl.box.com/s/biw4uelpmmcd…

The WashU calvary have arrived!! #ACR22 #Philly #ChooseWashURheum #Rheumatology Tarin Bigley Michael Paley, M.D., Ph.D. (moving to @Bluesky) Lisa Zickuhr Iris Lee MD MSCI

We are thrilled to have been part of a multi-institutional, multidisciplinary group to identify disease-associated T cells in #AnkylosingSpondylitis & Anterior #Uveitis that recognize antigens presented by HLA-B27, published in nature. (1/9)

Congratulations, Tarin Bigley , on receiving a Scientist Development Award from Rheumatology Research Foundation!!! 🎉🎉 #Rheumatology #Pediatrics #RheumPeds #SLE #Scientist @WUSTLPeds WashU Medicine Division of Physician-Scientists

Congratulations to our @WUPhysicianScientists Drs. Tarin Bigley, Jeffrey Brown & Drew Schwartz who received Young Physician-Scientist Awards from ASCI! Tarin Bigley @WUSTLPeds @WUDeptMedicine

Tarin M. Bigley, MD, PhD (Tarin Bigley), and Drew J. Schwartz, MD, PhD, were among 52 awardees who were honored with ASCI's 2024 Young Physician-Scientist Awards. Congratulations! pediatrics.wustl.edu/bigley-schwart…

Congrats to Selket Delafontaine (Selket Delafontaine) and Isabelle Meyts (Isabelle Meyts) on this great paper detailing how C-terminal domain variants in COPA lead to disease. It was great to collaborate with your group on this project. jci.org/articles/view/…

Great to get this interesting report about a phenotypic expansion of IKAROS GOF published. Congrats to Rachel Guess, Lynn Hassman, MD PhD Jeff Bednarski and George Harocopos. link.springer.com/article/10.100…

3/ 🇧🇪@isabelle_meyts,🇺🇸@MACattackLab, Tarin Bigley, 🇺🇸Carla Davis and Ruchit Rana identified heterozygous mutations (p.C1013S, p.R1058C and p.R1142X) in the C-terminal domain (CTD) of COPA in 6 children from 3 unrelated families with a syndrome of autoinflammation and autoimmunity

The Bigley and Paley labs just published our first senior author paper! This turned out to be a really cool collaboration. We used single cell RNA seq to identify the tropism of roseolovirus in vivo, in the thymus. Michael Paley, M.D., Ph.D. (moving to @Bluesky) thatdnaguy Eden Xue. 👏frontiersin.org/journals/immun…

Toth et al. @MACattackLab Test Account report spontaneous and stimulus-driven skin disease in a mouse model associated w/ locally increased Th17 that is partially dependent on IL-22 signaling hubs.la/Q02BnqTY0 #autoimmunity #immunodeficiency #inflammation

ICYMI: Explore a panel of ANRF Scholars and Yale School of Medicine alumni delving into arthritis and autoimmune disease treatments. They will cover advanced therapies and future directions in the field. ow.ly/rGe450SmruW

Our new paper led by Tihana Trsan, collaboration with Xavier Lab, investigating the link between FGFR1OP and Crohn’s disease. Deletion of FGFR1OP, a centrosomal protein, in mouse gut cells disrupts crypt architecture, causing inflammation and fatality cell.com/developmental-…

(1/7)Excited to see our latest manuscript in press at JCI insight (doi.org/10.1172/jci.in…)! This was a great extension of our continuing multi-institutional, multidisciplinary group to better understand pathogenic CD8 T cells in #axialspondyloarthritis & anterior #uveitis.

Tobin & @MACattackLab discuss new work from Jeanpierre et al (hubs.la/Q02HrT8N0) that identifies new germline variants in the gene encoding PTPN2 associated with loss of regulatory function, enhanced JAK/STAT signaling, and early-onset #autoimmunity. hubs.la/Q02HrPZN0

Really proud to share our lab's most recent publication led by former post-doc Kirill Shumilov. Early depletion of the gut microbiota after TBI alters the oligodendrocyte response and the important role T cells play in this process jneuroinflammation.biomedcentral.com/articles/10.11… #TBI NeurotraumaSociety

Shout out to DiPaolo Lab Stella Hoft on a great collaboration and new insight into the development of gastric cancer. sciencedirect.com/science/articl…