How to you measure temporal cellular dynamics from #singlecell #RNA-seq in an interpretable way? Neural Ordinary Differential Equations marry dynamical systems maths with #MachineLearning. Our new method "neuroVelo" extracts biology from #scRNA data: biorxiv.org/content/10.110…

Nice introduction for #scLENS. "A novel dimensionality reduction tool designed to overcome longstanding obstacles and empower researchers with greater accuracy and efficiency in single-cell RNA sequencing (scRNA-seq) data analysis" #scRNA rna-seqblog.com/sclens-data-dr…

Compared to the bioRxiv preprint last year 👇, new results include an integrative analysis with #scATAC/#scRNA co-assay data, demonstrating the added value of #GAGEseq in connecting CREs with target genes. 2/3 x.com/jmuiuc/status/…

Soki Kashima transcriptomics atlas via #scRNA-seq of n=63 pts w/RCC pre/post systemic therapies showing deep correlative analysis and need to investigate #RCC #TME as T-cell exhaustion phenotype and higher stress response associated w/#ICI responsiveness #ASCO24 OncoAlert

Could deep clustering method for #scRNA-seq data (scRISE) help tackle its complex underlying structures and the inherent noise in data acquisition? nature.com/articles/s4138…

New #scRNA-seq research: Deciphering the heterogeneity of differentiating hPSC-derived corneal limbal stem cells through single-cell RNA sequencing #cornea #limbalstemcells #cellsorting ow.ly/K3xB50SrNH3 Radboud University @TampereUniMET ISSCR Cell Press @MartinPeraJAX

Attending the #ISSCR2024 Annual Meeting? Check out the Virtual Human Development workshop! This workshop will explore recent advances in reconstructing human development using #OrganoidModels, #MathematicalSystems, and #SyntheticSystems. 🗓️ July 12, 2024 ⏰ 3 PM-6:30 PM 📍 Hall E, Level 2

Calling attendees for the #ISSCR2024 Annual Meeting in Hamburg! Don't miss the opportunity to explore how CorePlate™ technology is fueling groundbreaking research in hiPSC-derived 3D brain models. Poster #437 "Exploring the impact of dimensionality on electrophysiological

En route with the whole team to highly anticipated ISSCR annual meeting #ISSCR2024 in Hamburg. We are loaded with slides and posters (details in rest of thread), eager to share our progress in #stemcell #cardiobiology #genomics and #chromatin with old and new friends! 1/n

Senior Editor Madhura Mukhopadhyay will be at the #ISSCR2024 Meeting in Hamburg this week. Reach out to her to discuss your work on methods development in stem cells, organoids and embryo models.

The ISS National Lab is excited to be at #ISSCR2024! Join us tomorrow at 12:00 pm CEST for an Innovation Showcase with a panel of experts to explore the groundbreaking intersection of #stemcell research and low Earth orbit.

Good morning from Hamburg! From today on I will be representing "Signaling lab" at ISSCR congress in Hamburg. If you are interested in the generation of hDPSCs🦷 derived 3D structures for disease modeling, check out our poster!#ISSCR2024

Excited to attend #ISSCR2024! Can't wait to hear from the best in the field of Stem Cell Research! It's an honor to be representing both my labs (Briscoe lab James Briscoe & Hill lab Hill Lab)!

Another very interesting review introduces the technical attributes of single-cell RNA sequencing and spatial transcriptomics, and the core concepts of computational data analysis. #scRNA-seq #Computational_methodology #Spatial_transcriptome #Data_integration Genomics Proteomics Bioinformatics

Future of #omics meeting. Hk/shenzhen. Growing community of #scrna #ncrna #spatialtranscriptomics #proteomics nice research environment in #bgi

Nice description for researchers on how to approach the ScRNA omics

MUDI integrates #scHi-C and #scRNA-seq data to define the 3D-regulated and biological-context dependent cell subpopulations or topologically integrated subpopulations (TISPs). Nature Communications nature.com/articles/s4146…

Genuine question, why do we need multi-million scale scRNA datasets? What do we learn from that we can’t from just 100k? Shouldn’t replication be the focus?

The latest work from our laboratory is in press at Hepatology. Using mouse models, scRNA seq, and spatial transcriptomics, we show that the reparative activity of TREM2 macrophages is a mechanism by which bariatric surgery resolves MASH. journals.lww.com/hep/fulltext/9…

The October issue is live nature.com/nbt/volumes/42… On the cover, identifying a sparse, reliable set of biomarkers: Hédou et al. present a machine learning framework that selects the most reliable biomarkers from large multi-omics datasets go.nature.com/4aKotSr