Le Service d’Analyses Métaboliques (SAM) de TBMCore est une plateforme spécialisée dans la quantification de métabolites. Elle vient de se doter d’un nouvel équipement de pointe. sbm.u-bordeaux.fr/actualites/la-…

New review to read: DOI: 10.1146/annurev-biochem-052621-092014

A KI study published in Nature Metabolism today shows that a specific class of drugs that block mitochondrial function can reverse diet-induced #obesity, fatty liver and #diabetes in mice. #metabolism news.ki.se/new-drug-candi…

"Inhibition of mammalian mtDNA transcription acts paradoxically to reverse diet-induced hepatosteatosis and obesity" nature.com/articles/s4225…

Read our new study: nature.com/articles/s4225… Treatment of obese mice with small molecule inhibitors of mtDNA transcription (IMTs) leads to marked beneficial metabolic effects. The weight is normalized, the fat deposition in liver disappears and glucose homeostasis is normalized.

Online now! Inhibition of mammalian mtDNA transcription acts paradoxically to reverse diet-induced hepatosteatosis and obesity dlvr.it/T6FvFK

New paper from us on the in vivo role of the LRPPRC/SLIRP protein complex and its crucial role in mammalian mtDNA gene expression: academic.oup.com/nar/advance-ar… Congratulations Diana Rubalcava for great work! Thank you to all coauthors for a very nice collaboration.

This will be agreat meeting. Looking forward to attend!

Come join us! #CRC1218, #CECAD. We study how mRNAs encoding mitochondrial proteins are regulated.

News and Views from us on maternal transmission of mtDNA: rdcu.be/dSWDA In addition to the bottleneck mechanism and purifying selection in early oocyte development, elegant experiments show that purifying selection also occurs during postnatal mouse oocyte development.

BREAKING NEWS The 2024 #NobelPrize in Physiology or Medicine has been awarded to Victor Ambros and Gary Ruvkun for the discovery of microRNA and its role in post-transcriptional gene regulation.

#ResultatScientifique 🔎 | Sans la protéine Tono, la drosophile ne peut ni voler ni sauter… 🤝 CNRS 🌍 CNRS Provence et Corse IBDM ✍️ Frank Schnorrer 📕 Current Biology | buff.ly/4eN400T buff.ly/48d6OBW

New study from us: science.org/doi/10.1126/sc… High mtDNA copy number promotes lung cancer growth in the mouse, whereas mtDNA depletion in tumor cells reduces tumor growth. This tumor-intrinsic role for mtDNA can be exploited for development of future lung cancer therapies.

We have 1-2 PostDoc positions for enthusiastic researchers interested in mitochondrial biology. Apply here. #mitochondria #mitojobs ki.varbi.com/ny/what:job/jo…

Just over a week left to apply for a PostDoc position in mitochondrial biology with us. #mitochondria mitojobs ki.varbi.com/ny/what:job/jo…

We are excited to share our latest work on mechanisms that protect from mitochondrial dysfunction. Thank you to all collaborators and the 4th anonymous reviewer for supporting us. Matthias Mann Lab Nature Communications Florian Rosenberger nature.com/articles/s4146…

Want to know more about cardiac aging, mtDNA mutations, mitochondrial dynamics alterations and their links to senescence and inflammation? Check our latest review in Mechanisms of Ageing and Development: doi.org/10.1016/j.mad.…

#ResultatScientifique 🔎 Grâce à l’IA, les scientifiques peuvent désormais analyser automatiquement la forme et la structure des mitochondries avec une précision inédite ! ✍️ Mathieu Vigneau et Jean-Philippe Pradère 📕 Nature Metabolism | insb.cnrs.fr/fr/cnrsinfo/li…