RNAseq is commonly performed. We compared N=30 wild-type Bl6 mice to an N=30 heterozygotic knockout with a phenotype, and then downsized. We found you need at least an N= 8-12 to avoid a >50% false positive rate. A 2nd line confirmed the finding. biorxiv.org/content/10.110…

Dr. Xiaoming Lu, who has been a rock in my lab for the past 5 years or so, is relocating to the Raleigh-Durham NC area (Duke, UNC, NC State) with her family, and is looking for a new lab home. If anyone needs someone to build their lab around, she would be an amazing choice.

There's a lot of excitement about foundation models and their ability to learn biology 🧬💻 But current tools for perturbation prediction perform worse than simple linear models! We need more careful benchmarking to make progress. biorxiv.org/content/10.110…

Professor Edward H.Sargent a Canadian Scientist, who published many papers in top journals i.e., #science and #Nature. He wrote 10 tips on how to write papers. 𝗣𝗵𝗗𝘃𝗶𝗯𝗲 PhD Voice - Independently Run Labiofy #PhDposition #phdlife #PhD #postdoc #chemtwitter #Science #AcademicChatter