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Original Article HEAR-MHE study: Automated speech analysis identifies minimal hepatic encephalopathy and may predict future overt hepatic encephalopathy Bloom et al. #LiverX tinyurl.com/2fc2b353

Another engaging liver transplant journal club with the UMich transplant team! Talking about PTLD Rare, so literature is limited. Hard to know what to do 🤔 Decrease Tac? Switch to mtor inhibitor? Are we immunosuppressing too much in the first 6 months?

You may leave the institution where you trained (❤️ you MGH Division of Gastroenterology), but if you’re lucky, those mentors never leave YOU Thanks Ray Chung and JHEP Reports for inviting us to write our thoughts on the FUTURE of microbiome therapeutic trials in cirrhosis shorturl.at/X8Yl5

Dr Ponni Perumalswami Perumalswami delivering a masterclass on alcohol related liver disease We are hepatologists, but we CAN and SHOULD be prescribing medication to treat alcohol use disorder Naltrexone, NNT = 7! Hard to beat.

PROUD of University of Michigan medical student Gabe Rice for presenting our work on EEG as a way to optimize anesthesia management in liver transplant AASLD He has learned so much from this project. It’s been incredible to see his growth and the final product #mentorPROUD

I am VERY impressed by the work of Jessica Rubin on pain in cirrhosis #TLM2024 Since opioid safety initiatives, opioid prescribing is lower in cirrhosis and acetaminophen, NSAIDs, & gabapentin scripts are UP Now, how has that affected pain control for our patients? More to do…

EASLnews AASLD MASTERCLASS in beautiful Savannah ❤️ Gathering of next generation of leaders in hepatology🤩🤩 👉team science 👉building a team Networking among liver friends Sven Francque EASL Education

Family photo EASL Education AASLD MASTERCLASS Wonderful group

Flying home from AASLD and EASLnews Masterclass full of new inspiration and with many new friends 😊 So thankful that these two organizations prioritize young investigators as much as they do

📑 Validation of #MELD3.0 in 2 centers from different continents 🌎 In this study, MELD 3.0: 🔹Had highest mortality prediction in women 🔹But not superior to MELD-Na journals.lww.com/hepcomm/fullte…

Fibrates and other PPAR agonists are so hot right now 🔥🔥🔥 Here is a review of how they work, the evidence of benefit, and the bright future of this pathway in improving liver health journals.lww.com/hepcomm/fullte…

In pts w #hepaticencephalopathy on max Rx..how can we⬇️recurrence? #gutbrainaxis In our #FMT Phase 2 trial Journal of Hepatology funded by VA Research 🔑FMT capsule💊/💉enema➡️safe 🔑 FMT doses (1-2-3) >>placebo ⬇️HE recurrence 🔑 Donor engraftment matters!⤵️ pubmed.ncbi.nlm.nih.gov/39800192/

In #CTGjournal: The Misdiagnosis and Underdiagnosis of Hepatic Encephalopathy Patricia Bloom, MD ➡️ bit.ly/40naxJJ Patty Pringle Bloom, M.D. ACG Brian Jacobson Yasmin Hernandez-Barco, MD David J. Levinthal, MD, PhD Eugenia Shmidt MD Ashwani Singal

Gut R. gnavus may induce monoamine synthesis and neurotoxicity in some patients with #cirrhosis, causing #hepaticencephalopathy — revealing a possible therapeutic target for this understudied condition. News & Views from Patty Pringle Bloom, M.D. Michigan Hepatology nature.com/articles/s4159…

This trial by Patty Pringle Bloom, M.D. will be seen as one of the most important in the field of FMT - 💩 transplant - for #cirrhosis Does the 💩 engraft? Does the 💩 work (improved barrier function)? This is why P P B is the future journals.lww.com/hepcomm/fullte…

How reversible is hepatic encephalopathy after all In some cases, the damage persists Important paper: journals.lww.com/hepcomm/fullte… Hey, Marina Serper, MD, MS, maybe we should work on preventing HE?