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The U.S. finally approved artesunate, the gold-standard malaria drug, in 2020 but its price jumped to $30,000 vs. $5 abroad. Delays, red tape, and cost now put lives at risk. It’s time to fix rare disease drug access. statnews.com/2021/06/11/una…

Our crowd-sourced spreadsheet of controlled vaccine RCTs just hit 189 trials - spanning Adenovirus to Zika & 2.1 million participants. Every row links to the primary paper. More to come... docs.google.com/spreadsheets/d… cc Brad Spellberg

Forgotten but not gone: COVID rates in Canada have been low & declining for several months. However, the Omicron subvariant NB.1.1.8 has been more prevalent in SE Asia & it's likely we'll see more of that here in the near future. (Red = 2022-23; Yellow = 2023-24; Blue = 2024-25)

3 cases of #gonorrhea in Germany involved #resistance to the therapeutically important third-generation cephalosporins ceftriaxone and cefixime as well as high-level resistance to azithromycin. The pathogens were also resistant to ciprofloxacin and tetracycline.

Rolling clinical and epi updates for #mpox data from #SierraLeone. Watch for updated versions as additional data becomes available. Heartfelt thanks to our local colleagues in-country led by Dr. Jia Kangbai medrxiv.org/content/10.110…

🇨🇦 Canada has secured 500,000 doses of an updated H5N1 (avian influenza) vaccine. Here's a Canadian perspective in CMAJ on what this means, with colleagues from the Public Health Agency of Canada. Link: cmaj.ca/content/197/21… Public Health PHAC

An important commentary from Isaac and my colleagues at PHAC. As worried as I am about the situation in the US, I am at least assured that Canada is proactively addressing this threat. Gratitude for the evidence-driven preparedness efforts led by both PHAC and CFIA.

Sad news from Ontario: "It is with deep sadness that I confirm that an infant, born prematurely and infected with measles, has tragically passed away in southwestern Ontario." -Dr. Kieren Moore, CMOH tinyurl.com/mckw73bu

Update #1: Rolling clinical and epi updates for #mpox data from #SierraLeone. Watch for updated versions as additional data becomes available. Heartfelt thanks to our local colleagues in-country led by Dr. Jia Kangbai medrxiv.org/content/10.110…

To our American friends seeking data-driven and independent vaccine advice, please check out Canada’s National Advisory Committee on Immunization (NACI): Evidence-based insights & expert guidance.. 🇨🇦🇨🇦🇨🇦 Link: tinyurl.com/3ejd4b73

Loud claims are circulating that “no childhood vaccine was ever tested against placebo.” That is flat-out wrong. Here’s what the evidence actually shows. 🧵👇 1/

An independent group of experts has reviewed all available evidence on SARS-CoV-2's origins, including lab leak & natural spillover. Uncertainty remains. Only a methodical & rigorous approach (not partisanship or premature certainty) will lead us to credible answers.

Happy Canada Day 🇨🇦🇨🇦🇨🇦

God bless Southern Alberta

Measles cases in Ontario are on the decline (since May).

Canada has recorded the highest number of measles cases since achieving measles elimination status in 1998.

A person in northern Arizona has died from a case of bubonic plague, local health officials say. nbcnews.com/health/health-…

Rocky Mountain Spotted Fever (RMSF) has been reported in dogs in Long Point, Ontario. RMSF is transmitted through tick bites, so humans are also at risk. This infection can be severe. Take care to protect yourself & your pets. Info from 🇨🇦 Public Health PHAC: tinyurl.com/yc2ev4h2

Ontario is now seeing a sharp drop in measles cases, with the trend beginning in early May.

'tis the season. First identification of West Nile Virus in Toronto mosquitoes this year. cbc.ca/news/canada/to…