
Ann Boija
@boijaann
ID: 923620688258363392
26-10-2017 18:41:46
31 Tweet
222 Followers
102 Following

When his kindergarten teacher decided he was too tall and should skip ahead to 1st grade, Isaac Klein, now a postdoc and physician, didn't mind: "That means I'll start medical school a year earlier." Read on in this week’s #WhiteheadPostdocProfiles ow.ly/lyxv50keIgO


Biomolecular condensates pique drug discovery curiosity go.nature.com/2I9IqIj - find out more here about the drug discovery implications of transient liquid-like droplets made up of proteins and RNA in cells in this news story by Asher Mullard



A new study in nature led by Eric Guo & John Manteiga in Richard Young’s lab reveals that condensates play a role in splicing, an essential activity that ensures the genetic code is prepared for translation into protein: ow.ly/neKm50vqHwF MIT Biology MIT Science


How does a cell organize key steps in gene expression? Are transcription and RNA splicing organized in specialized condensates or “droplets”? What controls the transition from transcription to splicing? Check out latest Nature paper from our great team! nature.com/articles/s4158…

Furthering a new model of gene control, a study led by @krishna_shriniv of the Chakraborty Lab MIT ChemE Dept & Ben Sabari of the Young lab identifies threshold conditions that decide whether a condensate of transcription factors forms at a site on the genome: ow.ly/Y9v050vrUOB



Our work is published now! Great joy to work with Ben Sabari and team :)



Check out our new paper on how clinically important drugs are concentrated in nuclear condensates. So much fun doing this study together Isaac Klein, Richard Young and all collaborators. science.sciencemag.org/content/368/64…

Check out our review on biomolecular condensates in the nucleus. Online today Trends in Biochemical Sciences cell.com/trends/biochem…




Check out our review about Biomolecular condensates and cancer. Fun to write this together with Richard Young and Isaac Klein. authors.elsevier.com/c/1cNFW5TA51TI…

The latest paper from our lab is now online Molecular Cell. We used a histone replacement system and biochemical reconstitution to show the requirement of H3K14 acetylation for the expression of a set of genes that are essential for Drosophila development and tissue patterning.

Just three and a half days left to vote for Whitehead Institute's research in #STATMadness! Head to the link to cast your vote for papers on HIV and cancer drugs from the labs of Silvi Rouskin Silvi Rouskin and Rick Young Richard Young! MIT Biology MIT Science ow.ly/ulWs50DQkMX

It was touch and go for a while, but Whitehead Institute made a comeback and advanced to the second round of #STATMadness! Cast your vote here for a fantastic paper from Rick Young's lab Richard Young on how cancer drugs are distributed throughout the body: ow.ly/oTyC50DSXGM
