Dr. Lee Schwamm
@braindoc_mgh
SVP/Chief Digital Health Officer @YNHHealth + Assoc Dean, Digital Strategy & TX @YaleMed + MD @StrokeAHA_ASA = Digital Transformation to Democratize Healthcare
ID: 20685010
http://yalemedicine.org 12-02-2009 15:21:46
809 Tweet
2,2K Followers
228 Following
Read the primary paper to see all the secondary endpoints. AHA Science #ISC25
1/2: Great overview of adaptive designs and the various mechanisms available to clinical trialists to improve efficiency and ensure ethical enrollment AHA Science #ISC25
2/2: how do we bring the field forward to make adaptive designs the default not the exception? AHA Science #ISC25
Laura Gutierrez Quiceno from U Cinn receiving one of the Bernard J Tyson awards sharing her science on the reliability of ICD10 codes for AIS ((high) vs ICH (low). She is shown here with her 5 month old research assistant Olivia! AHA Science #ISC25
2/7 Sebastian Urday Northwestern Medicine as recipient of a Bernard J Tyson award for work in advanced MRI imaging of microstructural architecture in infarcted vs uninfarcted regions of cerebellum. Post infarction complexity correlates with cognitive performance AHA Science #ISC25
3/7 Bernard Ofosuhene, research coordinator at UMass Chan Medical School getting Bernard J Tyson awards sharing for using AI model to assess cognitive decline by ECG-derived cognitive age. AHA Science #ISC25
4/7 Abigail Teshome, recipient of Bernard J Tyson award for work related to social drivers of healthcare, differential impact of stroke legislation in RI on outcomes among all patient groups. Presenting on inequitable distribution of stroke centers. AHA Science #ISC25
Keith Churchwell joining the BJT award ceremony to support our awardees! AHA Science #ISC25
6/7 Sam Daniel working on integrating community health workers into care delivery to support equitable care outcomes. AHA Science #ISC25
1/7 Mazen Taman, PharmD and medical student at Brown presenting about his work on the association between platelet transfusion, antithrombotic therapy and risk of bleeding in SAH associated EVD. AHA Science #ISC25
7/7 Ruth Yanes-Benoga unable to attend ISC but a recipient of the Bernard J Tyson award! We miss you Ruth but can’t wait to see you in person at next year’s ceremony AHA Science #ISC25
Post hoc evidence of Clinical benefit of nerinetide in pts treated in early window of ESCAPE NEXT. No difference at 90 d but separation at 1 yr. No impact of Lytics. Potential biological mechanisms unclear. ACT Global will test this hypothesis prospectively. AHA Science #ISC25
Otaplimastat, an MMP-9 inhibitor, failed to improve outcome in two paired RCT pooled trials. Some signal in infarct growth rate and in higher baseline NIHSS. AHA Science #ISC25
THEIA study failed to demonstrate improved vision recovery of alteplase vs ASA in <4.5 hr but perhaps promising difference in recovery rates. Underpowered or ineffective???additional RCTs ongoing. AHA Science #ISC25
Excited to share a novel method for knowledge dissemination via synthetic podcasts created by Google’s NotebookLM from our guidelines and statements. Audience given QR code to the URL hosting the podcasts. medicine.yale.edu/neurology/divi… AHA Science Stroke AHA/ASA #ISC25
Celebrated amazing decade+ tenure of Merit cudkowicz as chair of Neurology Dept at MGH. Her remarkable leadership made the Dept like a 2nd home for all. Her inspirational leadership will continue as Exec Director of the new MGB Neuroscience Institute! Go Merit! MGH Neurology
Due to copyright, we used a private instance of Microsoft copilot within the AHA Science private cloud to preserve the intellectual property of the presenters. I encourage all of the readers to start experimenting with the various foundation models available.
