Brandon Chen, PhD
@brandontwchen
@theNCI K00postdoc with @KivancBirsoy |PhD with @Lyssiotislab & @Yatrikshahlab | organelle & metabolism
ID: 1032289295330172928
22-08-2018 15:32:01
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🚨New preprint available! Third and final in the #CRISPR screen series!🚨 👉🏻 Uridine-sensitized screening identifies genes and metabolic regulators of #nucleotide synthesis biorxiv.org/content/10.110… By A. Strefeler in collaboration with Pagliarini Lab Please RT 🙏🏻 🧵1/9
I'm excited to present a small method project of mine from Rutter Lab! Here we designed a dual-purification system to isolate mitochondrial subpopulations based on their proximity to membranous organelles. All constructs will be available on Addgene soon! journals.biologists.com/jcs/article/do…
🚀 New paper! 🧬✨Thrilled to share our latest work CDD press, pushing the boundaries of imaging inter-organelle contacts in vivo! Incredible effort by our talented postdoc Lucia Barazzuol, in collaboration with Alessio Vagnoni - now @alessiovagnoni.bsky.social and the Marisa Brini Lab. rdcu.be/efkYK🚀
Excited to share ‘Leucine Aminopeptidase LyLAP enables lysosomal degradation of membrane proteins’, by phenomenal superstar postdoc Aakriti Jain Aakriti Jain and amazing collaborators Rushika M. Perera, Guido Bommer, Charly Craik and James Olzmann: science.org/doi/10.1126/sc…
#CZBiohubNY welcomes its latest cohort of Investigators, including Katya Vinogradova and Kivanc Birsoy! They’re developing new tech to characterize + bioengineer immune cells—creating novel methods for early disease detection. rockefeller.edu/news/37564-two…
Excited to share new report from collaborative work from Delgoffe Lab and Patrick Jonker from our team on a novel metabolic suppressor of T cell function in tumors! rdcu.be/eiyIa 1/
A seriously awesome event (despite my tardy post)!! Thanks NYAS, NYU Grossman School of Medicine, fellow organizers (Lydia Finley, Marcus Goncalves), the *speakers for sharing awesome (and unpublished) science, and the attendees for literally packing the house! (Every seat reserved) 😃 *Speakers:
Beyond grateful to share that my main PhD thesis project, Targeting PIKfyve-driven lipid metabolism in pancreatic cancer (Lyssiotis Lab Arul Chinnaiyan), has just been published in nature! U-M Rogel Cancer Center Rogel and Blondy Center for Pancreatic Cancer University of Michigan Medical School Michigan Pathology Michigan Research UMich CMB
Big shout out to Caleb Cheng for this impressive body of work! One of the smartest and grittiest scientist I've ever had the pleasure to interact with! Can't wait to see what's next in house for you!!!!
The Sable Award lecture at METPHYS2025 was really remarkable! Tremendous congratulations to this years exceptional member of our community Kivanc Birsoy
excited to share our latest work now online Nature Metabolism, led by Kyle Flickinger, where we unravel a mechanistic basis for the conditional essentiality of NADK, one of the many interesting hits from our previously reported CRISPR screening with HPLM rdcu.be/ekpu6
#Preprint alert! Kevin (Yan-Ting) Chen, a brilliant GSK Graduate School graduate student and NCI F99/K00 awardee, identifies a novel, post-transcriptional checkpoint on intratumoral T cell function: biorxiv.org/content/10.110…
We are delighted to share our new study on metabolic dependencies in group-3 medulloblastoma! Thanks to an awesome team of collaborators who made this possible! Lyssiotis Lab Shah Lab The Sontag Foundation Carl Koschmann Sophia Lunt U-M Rogel Cancer Center Michigan Pathology cell.com/cancer-cell/ab…
