🔥The 9th Round of Easy Loan, Earn $40 Reward is in progress❗️ ⏰ Promotion Period: January 15th - Feburary 15th, 2025 👉 Register now and check more details at gate.io/campaigns/358

Joining forces with Babak Alipanahi, Hormozdiari Lab, Aiden M Sababi & Mehran Karimzadeh to bring you Exai-1; a multi-modal cell-free RNA foundation model for blood surveillance and liquid biopsy. Kudos to the broader exai bio team for getting this across the line. biorxiv.org/content/10.110…

So excited to be speaking at #ted2025 this year! I’ll be talking about the intersection of AI and biology 🧬

Next Tues (4/15) at 4PM ET we will have Garyk Brixi present "Genome modeling and design across all domains of life with Evo 2" Paper: biorxiv.org/content/10.110… Sign up on our website for zoom links!

Is the genome just a bag of genes? A new paper in Science Magazine now reports that for two thirds of an organisms' genes the position along the chromosome is actually very tightly constrained! Amazing work from my favorite night scientist Martin Lercher and his team!

What could scaling unlock for biology? Introducing ProGen3- our next AI foundation models for protein generation. We develop compute-optimal scaling laws up to 46B parameters on 1.5T tokens with real evidence in the wet lab. +we solve a new set of challenges for drug discovery

There is no rest when training models at scale. You spend some days in an industrial forge, sparks flying as the machines clang and sputter. You spend other days in the operating room, performing a delicate surgery for a newly discovered condition, hoping the patient recovers

I'm joined with Anna Marie Wagner, a real expert in AI and bio, and we’re talking about some of the incredible speakers coming to #SynBioBeta2025 this year. One of the people we are especially excited about is Brian Hie from the Arc Institute. Brian is doing groundbreaking work

Thrilled that our work "Sidechain conditioning and modeling for full-atom protein sequence design with FAMPNN" has been accepted to ICML 2025! 🥳 Looking forward to connecting with the ML and comp bio communities in Vancouver this July! :)

Catch Talal Widatalla and Richard Shuai at ICML!

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For neurodegenerative diseases like Alzheimer’s and Parkinson’s, treatment options are scant. New research identifies a promising access point to therapeutics. news.stanford.edu/stories/2025/0…

.@ArcInstitute is redefining how biomedical research is conducted. Looking to harness body-brain communication to counteract human disease, our lab is exploring new approaches through shared tools & collaboration. Read more in our Q&A. arcinstitute.org/news/news/chri…

This is beautiful work, congrats to the team!

Over the last 2 weeks, I took a deep dive into Evo 2, Arc's Genomic Foundation model. But, I couldn't find a crisp primer on Evo 2 that covered the decisions for the ML architecture, the inference-time scaling results or the mechanistic interpretability results. So, I wrote one!

Today is my first day as Writer-in-Residence at Arc Institute I'll be writing about the Virtual Cell, genome editing + much more. Grateful for the invitation to spend my summer here and learn more about AI+Bio!

🎉New preprint!🎉 Extremely excited to share CryoBoltz❄️⚡️, led by superstar Rishwanth Raghu! We develop a multiscale guidance recipe to steer structure prediction models (e.g. AlphaFold3 / Boltz-1) towards experimental cryo-EM density maps, including heterogeneous,

Introducing Arc Institute’s first virtual cell model: STATE

Cells are dynamic, messy and context dependent. Scaling models across diverse states needs flexibility to capture heterogeneity Introducing State, a transformer that predicts perturbation effects by training over sets of cells Team effort led by the unstoppable Abhinav Adduri

Register for this challenge and congrats to the team for making this available to the community!

Stanford biochemist Lingyin Li is studying a tumor-fighting “miracle molecule” that could one day inform therapies for cancer, as well as autoimmune, neurodegenerative, and age-related diseases: stanford.io/3I5xqfx