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The new integrative analysis of #scRNAseq data by Martín E. García Solá and colleagues reveals new pseudo-temporal trajectories of #mammary epithelial cell populations. link.springer.com/article/10.100…

Lab's newest paper looking at whole genome sequence and gene expression to compare breast cancer models with differential metastasis properties is now available. rdcu.be/cjV4q

New research led by MSU scientists is bringing fresh insight to the Inflammatory Bowel Disease (IBD) table—an unexpected connection between specialized cells in the gut and the genes involved in IBD. Read more here: bit.ly/3CD1RlI #InflammatoryBowelDisease #IBD

Tons of new insights in this new paper by @dralexswarbrick and team analyzing breast cancer samples at single-cell resolution, including fascinating potential interactions between cancer-associated fibroblasts and immune cells! nature.com/articles/s4158…

Preprint deposited. We (meaning mainly Matt Swiatnicki) showed PTPRH normally dephosphorylates EGFR and a mutant version allows for elevated EGFR phosphorylation. As a result, lung cancer that is EGFR wild type but PTPRH mutant responded to EGFR TKIs. biorxiv.org/content/10.110…

Spartan researchers are working to make new discoveries for breast cancer patients. Eran Andrechek, Ph.D. uses bioinformatics and genetic models to examine the mechanisms involved in breast cancer progression. Who will fight cancer? #SpartansWill #MSUCancerResearch

Dr. Joan Brugge (JOAN BRUGGE) and her team at Harvard Medical School (Harvard Medical School) describe an in-depth analysis of molecular and functional heterogeneity among subclonal populations derived from a single #TNBC cell line. Take a look here! 👉 go.nature.com/3El05FW

Now Cancer Cell: authors discuss emerging technologies for functional precision medicine, and limitations and challenges to using these assays in clinical trials necessary to determine whether functional precision medicine can improve outcomes. Anthony Letai MD PhD @AlanaWelm

Couples matched with Aaron Chow, DO PhD at our #1 choice! Excited to start the next chapter of our lives at The Ohio State University! Ohio State Internal Medicine Residency #DoubleDocs #Match2022 #IMProud

Excited that our department will have a search for a tenure track faculty member this fall in cancer biology - with no stipulations that they need a K99. Doing the admin training this week and then writing an advertisement. Can't wait to see who we get to bring in!

What are the big-data analyses that transformed the understanding, diagnosis & treatment decisions of cancer? The next challenges to push this even further? & a compilation of all the major big-data resources to assist in this. Our review's full version: tinyurl.com/mrxpjaad

EGFR phosphorylation mis-regulated by mutant PTPRH in lung cancer. A long time in the works, but happy to see Matt's thesis work published at PLoS Genetics. journals.plos.org/plosgenetics/a…

So proud of Laura Harding-Jackson for matching her number 1. Well deserved! Looking forward to going to a OSU vs Michigan game.

Congrats to my former lab mate, Dr. Rennhack @JonRennhack for his new publication that provides insight into CRC development. Very interesting work!

Commentary in Cancer Cell: challenges & opportunities in modeling #aging & #cancer. @OlgaAnczukow @jeffgenome LisaCoussens@CoussensLab George KUCHEL Polyak Lab Jennifer Trowbridge @duyguucar @shengli_jax @politikaterina @AnnaLisaLucido1 & others The Jackson Laboratory cell.com/cancer-cell/fu…

Heart Failure-Related Cardiogenic Shock is a distinct entity needing a unique treatment pathway 💥Pleased to share our piece on management strategies for HF-CS JACC Journals #JACCHF Navin Kapur Vanessa Blumer, MD, FACC BiykemBozkurt Marwan Jumean, MD Nir Uriel, MD MSc Maya Guglin 📎 sciencedirect.com/science/articl…

The review from Eran Andrechek team explores the molecular landscapes and characterization of breast cancer research models by comparing recent published multi-omics data and analysis. link.springer.com/article/10.100…

Today Cell, Cancer Cell and Cell Reports Medicine are pleased to publish the 1st wave of Pan-#Cancer multiomics papers looking at over 1000 patients across 10 #tumor types from National Cancer Institute Clinical Proteomic Tumor Analysis Consortium #CPTAC (1/n) Cancer Cell Cell Reports Medicine #openaccess

Congratulations to our 2024-2025 OhioStatePath Chief Residents, Drs. Aaron Chow Aaron Chow, DO PhD and Lokman Cevik! Looking forward to your leadership! #PathTwitter #pathx

Had an amazing time at my first #ASCO24 with Hyunwoo (Tony) Kwon, MD PhD Jose Forero M.D. Anthony Mansour Looking forward to future meetings as an official heme/onc fellow. Ohio State Internal Medicine Residency The Ohio State University Wexner Medical Center