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Delighted to see the official cover of When Your Neurons Dance #WYND Routledge Books Taylor & Francis Coming late summer 2025.

Researchers review metabolomics in #Parkinsons, exploring alteration of metabolites in the TCA cycle, pentose phosphate pathway, kynurenic network, & redox system mdpi.com/2218-1989/15/3…

The vaccine against Shingles helps protect against dementia, results of a natural experiment, adding to prior evidence "implications are profound" New nature nature.com/articles/s4158… nature.com/articles/d4158…

Infections and neurodegenerative diseases many years later….where have you heard this before?

Patrik Brundin MD PhD Yes we have also seen that early infections increases the risk of Parkinson’s disease

Spring break in Michigan might be cold, but the beauty is unsurpassed! #LakeMichigan #PureMichigan #HollandMichigan #Macatawa

Interesting: Genes associated with primary cilia, non-synaptic sensory & signaling organelles, are upregulated in cortical neurons in both early & late stage #Parkinsons patients; Tet2 loss & enhanced ciliogenesis suppress α-synuclein pathology actaneurocomms.biomedcentral.com/articles/10.11…

Tiderna förändras. Jag minns när en EPA traktor knappt klarade 30 km/tim!

Mats Melin, ordförande för Coronakommissionen och tidigare domare i Högsta domstolen, beskriver Sveriges pandemistrategi första året. Nytt program från UR: urplay.se/program/239265…

Just like in our happy relationship, my wife Lena emphasizes sex differences in her research! 😃

"We have to cure this pernicious condition, and we have never been closer to finding a cure." Catch our chairman of the charity’s development board Will Cook discussing our #walkforacure campaign: buff.ly/9ErsB8j

Gain Therapeutics Gain Therapeutics researchers & collaborators report Gaucher’s fibroblasts (GBA1 variants) have increased Tau accumulation (vs control fibroblasts) & pharmacological enhancement of GCase reversed this effect; Implications for #Parkinsons? nature.com/articles/s4159…

A personal view on gene therapy for #Parkinsons is a timely & succinct overview of both the progress & challenges - weekend reading! thelancet.com/journals/laneu…

Twelve Years of Drug Prioritization to Help Accelerate Disease Modification Trials in Parkinson’s Disease: The International Linked Clinical Trials Initiative—Richard Wyse, Tom Isaacs, Roger Barker, Dimitri Krainc, Simon Stott The Science of Parkinson's, Patrik Brundin MD PhD linkedin.com/posts/krzyszto…

This is the inflammatory subtype of depression. 🧵1/10

Using PASADENA study data, Gennaro Pagano & Roche collaborators find that the time-to-event approach may mitigate the potential confounding effect of symptomatic therapy on MDS-UPDRS Part III in #Parkinsons clinical trials exploring disease modification nature.com/articles/s4153…

“Is the solution not to allow the rest of the world to publish? We live in a digital world. Surely, it doesn’t matter how many papers are being published” - Ritu Dhand The solution is to move aware from publishing in "journals". That model is long dead theguardian.com/science/2025/j…

England-Sweden 2-2 in extra time. English fans not impressed. #Euro2025

Nice editorial in the The Lancet Neurology on accelerating the path towards a cure for #Parkinsons - the michaeljfox.org "Targets to Therapies" (T2T) initiative gets a mention, as does the new Alzheimer's Research UK & Cure Parkinson's collaboration - lots of activities thelancet.com/journals/laneu…

#WorldBrainDay We believe there won't be a single silver bullet for this disease. Each patient will likely require a mix of medicines at different stages of disease, and with more options available, this precision medicine becomes possible Patrik Brundin MD PhD linkedin.com/posts/krzyszto…