🔥The 9th Round of Easy Loan, Earn $40 Reward is in progress❗️ ⏰ Promotion Period: January 15th - Feburary 15th, 2025 👉 Register now and check more details at gate.io/campaigns/358

What if 1 million scRNA-seq libraries can be prepared within $1k? Here we go 👉 21 million cells from 623 mouse tissues, spanning 5 life stages & 3 genotypes, all in a SINGLE study by ONE remarkable student Zehao Zehao Zhang from our lab Rockefeller University! shorturl.at/epsz7

In collaboration with Reuben Saunders, Jonathan Weissman's Lab, and Xiaowei Zhuang, we are very excited to release Perturb-Multi: a platform for pooled multimodal genetic screens in intact mammalian tissue. Check it out! biorxiv.org/content/10.110…

In collaboration with William Allen and Xiaowei Zhuang, we have developed Perturb-multi: biorxiv.org/content/10.110…

Why do quiescent neural stem cells look so much like neurons? 🤔 We showed that quiescent neural stem cells transiently adopt a neuronal identity to coordinate reactivation across the CNS! See our latest preprint here: biorxiv.org/content/10.110…

Organs age at different rates. This was discovered in genetically identical animals through research by the Tony Wyss-Coray Lab. Ongoing human studies build on these findings, revealing how organ-specific aging links to diseases like dementia and heart failure. washingtonpost.com/wellness/2024/…

Finally out in Science Magazine! Utilizing the cost-effective EasySci to profile 21 million single-cell transcriptomes across five life stages and diverse sexes/genotypes, we reveal aging as distinct, development-like transitions, with dramatic cell population changes in specific

Could one envision a synthetic receptor technology that is fully programmable, able to detect diverse extracellular antigens – both soluble and cell-attached – and convert that recognition into a wide range of intracellular responses, from transgene expression and real-time

Congratulations to Professor Sir Tony Kouzarides – who was presented with his award insignia at Windsor Castle’s Investiture ceremony yesterday. Sir Tony was awarded a knighthood for his services to healthcare innovation and delivery. Read more here 👉milner.cam.ac.uk/milner-directo…

I’m pleased to announce the publication of our single-nucleus atlas of adult neurons from wild-type and long-lived, better performing insulin receptor (daf-2) mutants. DOI: 10.1016/j.xgen.2024.100720 - see the blue place for thread cell.com/cell-genomics/…

New publication from our team suggesting a new framework for understanding #synapse #development and diversity in the mammalian #brain in Nature Neuroscience nature.com/articles/s4159… European Research Council (ERC) Fondation pour la Recherche Médicale CIRB_CdF Join us where the sky is blue for more infos !

🎆4 years in the making! Thrilled to share the 1st spatial single cell aging clock⏰ nature nature.com/articles/s4158… We use #AI + spatial transcriptomics to discover what makes some cells age faster/slower in the brain🧠 Led by Eric Sun; awesome collaboration w/ Brunet Lab 🧵

Fantastic thread from Eric Sun! Spatial transcriptomics of brain aging and 'spatial aging clocks' identify cells that have pro-aging or pro-rejuvenating effects on their neighbors! Congratulations Eric and all authors!!🙌 Awesome collaboration with James Zou!

Thank you Stanford University Stanford Knight Initiative for Brain Resilience for highlighting our brain aging paper w/ Brunet Lab! nature.com/articles/s4158… brainresilience.stanford.edu/news/blight-or…

We have moved to brunetlab.bsky.social Check our new content there!!

I am excited to present our new study out in Nature Medicine where we discover a novel synaptic protein biomarker to predict if and when someone will get Alzheimer’s disease dementia. Part 2/3 from my PhD work in the Tony Wyss-Coray lab. 🧵1/12 Full study 🔗: nature.com/articles/s4159…

Excited to share our first anti-aging intervention study, led by brilliant Zehao Zehao Zhang, Alex Alex Epstein, and Chloe Chloe Schaefer from our lab at Rockefeller University! With a cost-effective spatiotemporal analysis pipeline, we identified the aging-associated cell

I’m very excited to be joining MIT Biological Engineering MIT Dept of BE as an Assistant Professor and the Ragon Institute Ragon Institute as a member in January 2026! I will be recruiting students and postdocs (see more info below).

Congratulations to Eric Sun for starting as an assistant prof at MIT MIT Dept of BE! He is a superstar in #AI for bio and aging🚀 Check out his group! Very fortunate to co-advise Eric w/ Brunet Lab over the last 5 years at Stanford!

Happy to share our recent review as part of the Cell Stem Cell Hallmarks series, co-authored with friends/colleagues/collaborators, Anne Brunet (Brunet Lab) and Peggy Goodell (@Goodell_lab) Hallmarks of stem cell aging: Cell Stem Cell cell.com/cell-stem-cell…

I'm thrilled to share our new study out in Nature Medicine! We show that a blood test can estimate how aged or youthful one’s organs are and that these organ ages predict future disease and lifespan. Final paper from my PhD in the Tony Wyss-Coray lab. 🧵1/12 🔗 nature.com/articles/s4159…