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Plus in the paper roundup: 1) iPSCs for aortic valve disease ❤️ Gladstone Institutes Deepak Srivastava 2) Single-cell of gut development 💻 MRC WIMM David Fawkner-Corbett 3) Spice and blood stem cells 🌶 EinsteinPhD Albert Einstein College of Medicine - Official 4) Non-canonical wnt in the gut 🧫 Heiko Lickert Helmholtz Diabetes Center (HDC)

Super excited to be a part of this work, in which we review cell type specific microRNA therapies for myocardial infarction: stm.sciencemag.org/content/13/580…

Some provocative ideas with Alberto Hernández Barranco and Laura Nogués CNIO Stop Cancer , still much work to do in this field, Could EVs Contribute to Generation or Awakening of “Sleepy” Metastatic Niches? frontiersin.org/article/10.338…

So excited to announce our new review, written by Pam Graney, PhD Naveed Tavakol, PhD Alan Chramiec Kacey Ronaldson-Bouchard, is out in Cell Press iScience journal & describes progress in modeling tumor metastasis with regards to immune cell contributions! Check it out: sciencedirect.com/science/articl…

Please RT & spread widely: our lab is hiring three research assistants for work in various tissue engineering projects. If interested, please see links below on how to apply: > opportunities.columbia.edu/en-us/job/5135… > opportunities.columbia.edu/en-us/job/5134… > opportunities.columbia.edu/en-us/job/5134…

Glad to kick off today ISEV2021! co-chair with Lucia Languino in concurrent Session 1, How are EVs involved in cancer pathogenesis? looking forward to #ISEV2021!! Excellent talks ahead!! @IsevComms ISEV

Congratulations to Gordana for winning the popular prize at the EuropeanPatentOffice #InventorAward ceremony!!! We are so, so proud, and thank you to all that voted! Serbia in USA Марко Ђурић Columbia BME Columbia Engineering

Happy Thanksgiving!! I am happy to share our latest work, role of tumor-secreted exosomes in lymph node pre-metastatic niche formation, NGFR goes out!! I am thankful for everyone involved and thank YOU for reading this! enjoy! GEIVEX ISEV CNIO nature.com/articles/s4301…

Had the opportunity to preview some great work from Joe Mazzulli's lab looking at alpha-synuclein in neurons derived from patients with Parkinson's disease - out today in Neuron Our preview: cell.com/neuron/fulltex… Stojkovska et al.: cell.com/neuron/fulltex…

The Tissue Engineering Resource Center #TERC is so excited to announce "#ScienceSimplified," an online resource for introducing #TissueEngineering concepts and major innovations in the field to young, future bioengineers: nextgenterc.com/science-simpli…

Check out Xiaokan Zhang's new bioRxiv "STK25 inhibits PKA signaling by phosphorylating PRKAR1A" from the Barry Fine Lab and members of our cardiac team! biorxiv.org/content/10.110… Columbia BME ColumbiaCardiology Columbia Stem Cell Initiative (CSCI) Bryan Wang Trevor R. Nash Bohao Liu Bobbie Lock

Our trainees Bryan Wang and Margaretha Morsink are attending American Heart Association #BCVS2022! Check out poster P1007 today about the functions of BAG3 in cardiac fibroblasts:

Excited to see some amazing science! AHA Science

FineLab celebrating two huge graduations! Congrats to Lori Luo for heading to UCSF MSTP next year and to @bryanzwang for graduating from the PhD program from Columbia University VP&S MD-PHD Program! Thanks to Baekjong for amazing bbq!

Delighted to share the last piece of the story from my PhD work, now out in Cell Reports - we leverage the spatiotemporal advantages of light to direct mesenchymal differentiations 💡

Check out our new analysis tool & publication led by Youngbin Kim now out in IEEE Open J of Engineering in Medicine & Biology: "BeatProfiler" - a machine learning platform for classification of in vitro cardiac muscle functions, for cardiovascular disease modeling & drug testing Paper: ieeexplore.ieee.org/document/10490…

Amazing work by Youngbin Kim! If you do any sort of iPS-cardiomyocyte analysis please check out this completely open source software, which completely changed how we process contractility videos.

Our manuscript detailing a mechanism of cardiac fibrosis caused by the loss of BAG3 is now out in Journal of Clinical Investigation! Congrats to co-leads Bryan Wang & Margaretha Morsink, & grateful for collaborators in the @GOuditresearch, FineLab, & Seidman labs! jci.org/articles/view/…

BAG3 mutations cause dilated cardiomyopathy but most research has focused on its function in heart muscle cells rather than other cardiac cell types Bryan Wang Margaretha Morsink Gordana Vunjak-Novakovic & team used engineered heart tissue to reveal role of BAG3 in cardiac fibroblasts in fibrosis: