Masterclass 😭 #bestmemeever

REVIEW Ozanne, Constancia et al. (Cambridge University) discuss sex differences in response to pre-conceptual & in utero environments, detailing the mechs underlying #inheritance of metabolic traits & how they can later manifest as metabolic diseases. nature.com/articles/s4225…

VMNdm Ghrh neurons provide complex dynamic, sex-specific input to the brain glucose-regulatory network #hypoglycemia sciencedirect.com/science/articl…

World’s Most Iconic Graduate School Recommendation Letter: John Nash, a prodigious mathematician known for his groundbreaking work in game theory and other mathematical disciplines, submitted an application to Princeton University’s esteemed mathematics graduate program in 1948.

The (leaky) gut brain axis enabling neuroinflammation is a reproducible finding in mouse studies. Will these findings yield druggable targets for human disorders? biorxiv.org/content/10.110…

.INNODIA researchers from Lahesmaa Group & Elo Lab demonstrate serum proteomics differences and associations with #betacell function and #type1diabetes in a pan-European study to arrest #T1D tinyurl.com/2vfu3vrv 🔓

Focus on the ever-growing evidence of #cardiovascular protection offered by #incretin-based therapies, reviewing CVOTs and real-world data of #GLP-1 receptor agonists and early clinical trials of novel dual and triple co-agonists. #T2D #GLP1RA #CVD. tinyurl.com/ye25sy84 🔓

SERCA2 deficiency leads to glucose intolerance and reduced proinsulin processing in beta cells via alterations in the spatial regulation of prohormone trafficking and processing enzyme maturation tinyurl.com/7hywn39a 🔓

SGLT2i and GLP-1RA show benefits as adjunct Tx in #T1D w/ SGLT2i providing CV & renal benefits, but w/ ⬆️ ­risk of DKA & UTI @AlamUazman Institute of Life Course and Medical Sciences @TriNetX WeillCornellQatar Matty A 🔓 tinyurl.com/msf56j3x #TopTweetTuesday

Very interesting new study about central versus peripheral actions of liraglutide👇

« Our survey demonstrates that non-native English speakers, especially early in their careers, spend more effort than native English speakers in conducting scientific activities, from reading and writing papers and preparing presentations in English » journals.plos.org/plosbiology/ar…

Our new review is out, taking a retrospective look at the evolution of dual incretin agonists. We also spend some time discussing if and how GIP matters for new drugs like tirzepatide. Matthias Tschöp Timo Müller Cell Metabolism urldefense.com/v3/__https://a…$

A new review, the dual GIPR-GLP-1R co-agonists exemplified by Tirzepatide move to the front of the stage #T2D #obesity #weightloss Cell Metabolism cell.com/cell-metabolis…

Our lab is hiring postdocs for 3 funded projects on hypothalamic development and function using brain organoids and mice with advanced microscopy, single cell ‘omics, in utero electroporation. If interested, pls email your CV+cover letter to Dr. Kurrasch ([email protected]).

🧠💊Sharing new work by Ruth Hanssen and @tittgemeyer showing that the GLP1 agonist liraglutide restores impaired associative learning in people with obesity. Online now in Nature Metabolism nature.com/articles/s4225…

Online now! Liraglutide restores impaired associative learning in individuals with obesity dlvr.it/StnLWN

#OpenAccess in Cell Reports Medicine Metabolic classification suggests the GLUT1/ALDOB/G6PD axis as a therapeutic target in chemotherapy-resistant #PancreaticCancer cell.com/cell-reports-m… Metabolomics profiling of pancreatic cancer organoids identifies two subtypes - high glucose

[💼JOB ALERT] L'Institut Pasteur de Lille, fondation privée indépendante, reconnue d’utilité publique depuis 1898, recherche sa #directrice générale / son #directeur général. Retrouvez toutes les informations sur le poste👉 tinyurl.com/5f7uathm #santé #recherche #prévention

Congratulations to Patrik Rorsman FRS - pancreatic islet electrophysiologist extraordinaire!