We have a pleasure to introduce 4-cyano-N-trifluoromethoxypyridinium triflimide, a trifluoromethoxylation reagent enabling direct C-H late-stage trifluoromethoxylation. Discover more at: cfplus.cz/4-cyano-n-trif… #trifluoromethoxylation #fluorine #medicinalchemistry #brnoregion

We are excited to announce that we developed a novel technology for protein bioconjugation via their tryptophan residues. See press release: cfplus.cz/news/detail/ne… Big thanks to our co-workers and to JIC - business with a purpose for support! # bioconjugation #proteins # drugdiscovery #brnoregion

Site-selective bioconjugation of tryptophans - a new tech from CF Plus Chemicals, Petr Beier🇨🇿🇪🇺🧪📝 / IOCB Prague, and #IMIC. #protein #bioconjugation #structuralproteomics

New synthesis of N-fluroalkyl pyrroles: Rh-catalysed transannulation of N-fluoroalkyl triazoles with various vinyl ethers leads to N-fluoroalkyl pyrroles. More at cfplus.cz. #cfpluschemicals #fluorine #medicinalchemistry #drugdesign #brnoregion #IOCBPrague

Facile access to novel regioselectively substituted N-fluoroalkylimidazoles with Rh-catalysed chemistry. Valuable motifs in pharmaceutical and agrochemical products. #cfpluschemicals #IOCB #imidazole #triazole #medicinalchemistry #agrochemistry

Fast Fluoroalkylation of Proteins Uncovers the Structure and Dynamics of Biological Macromolecules pubs.acs.org/doi/10.1021/ja…

#taiwaniacapital investuje 200 milionů USD do CEE firem. Až 80 % z toho půjde do ČR, SR a LTV. Na JICu jsme jim představili #brnoregion, investory z Jihomoravský kraj i dva #startupy NenoVision a CF Plus Chemicals Y Soft Ventures Karel Obluk #purpleventure bit.ly/3tp6VHM

Pd-catalyzed difluoromethylations of aryl boronic acids, halides, and pseudohalides with ICF2H generated ex situ (Skrydstrup Group iNANO - Interdisciplinary Nanoscience Center Department of Chemistry - Aarhus University) #OpenAccess onlinelibrary.wiley.com/doi/10.1002/ch…

BREAKING NEWS: The Royal Swedish Academy of Sciences has decided to award the 2022 #NobelPrize in Chemistry to Carolyn R. Bertozzi, Morten Meldal and K. Barry Sharpless “for the development of click chemistry and bioorthogonal chemistry.”

Proud to be producers of fluoroalkyl azides which are helping to diversify leads all around the world. #NobelPrize #Chemistry 👉cfplus.cz/science/fluori…

Without notable #nobelprize awarded work of Carolyn Bertozzi #BarrySharpless and #MortenMeldal, this technology would not be possible. Thank you all.

Interested in click chemistry reagents? Discover our portfolio of fluoroalkyl azide solutions just for your project. 👉 cfplus.cz/fluoroalkyl-az… #clickchemistry #chemistry #leaddiversification #nobelprize #MortenMeldal #BarrySharpless

Proud to be producers of fluorinated azides for click chemistry. Check out more 👉cfplus.cz/science/fluori… #nobelprize #MortenMeldal #BarrySharpless #CarolynBertozzi #chemistry #clickchemistry

Click chemistry is a powerful tool for diversification but also for a better understanding of biomolecules. Explore more: cfplus.cz/clickable-19f-… #biomolecule #probes #nobelprize #CarolynBertozzi #MortenMeldal #BarrySharpless

Congratulations to Lukas Fojtik on the BIOCEV_SCIENCE PhD Student Publication Award. Great collaboration with the Beier lab IOCB Prague and CF Plus Chemicals. Thanks #GAČR + Horizon2020Projects for financial support and BIOCEV_SCIENCE + HPST/Agilent Technologies for sponsoring this award.

Tried out DSM2 from CF Plus Chemicals in vitro, works very well, ~1000 type 2 X-links off 350 kDa protein (RNAP, obviously). In vivo next. Technically the name is Disuccinimidyl succinate; on account of 2 CH2 groups in the linker I call it DSM2. Easier. #XLMS #proteomics