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Today is #WorldCancerDay and we are committed to knowing how DNA damage is repaired to prevent cancer and how we can develop new chemotherapeutics. But this day is about the brave patients who are fighting this disease day in day out #IAmAndIWill MedUni Wien

Today we celebrate #WomenInScience, in our lab and across the world. Over the last year we have lived through trying times - not only a pandemic but the lab moved institute. Yet these strong women are still smiling. It's amazing to work with you all 👩🏽‍🔬🧪🧫🧬🔬 Women in Science Day

Today is #WorldCancerResearchDay. Curious about our research in understanding cancer biology? 👇🏻 Here is a 🧵 highlighting some of our projects and talented researchers

1/6 Excited to share our work on the #DNArepair requirements of #CRISPR precision editing by prime editing! We identify that loss of the 🧬 Mismatch Repair pathway improves prime editing efficiency and fidelity. A 🧵: biorxiv.org/content/10.110…

Happy Christmas from the Loizou lab 🎄🎅 Enjoy your time with family and friends over the holidays and dont get left #HomeAlone like Anna (Schrempf) Hanzl

In their new Nature Communications paper, researchers from CeMM Adjunct PI & MedUni Wien Group Leader Joanna Loizou (Joanna Loizou) show how the #DNArepair pathway in a cell plays an essential role in the #PrimeEditing technique, a variant of #CRISPRCas ✂️🧬 ➡️ cemm.at/news/n/advanci…

Gender equality will enhance research around the world nature.com/articles/d4158…

Thrilled for our Orpinolide story to see the light of day! Huge thanks to the @georg_e_winter lab, Waldmann lab, Luca Laraia and everyone that contributed Hana Imrichova (Novotna), @FabianFrommelt, Laura Depta, Andrea, Chrysanthi Kagiou, Thomas, Cris Mayor-Ruiz, Superti-Furga Lab and Sonja Sievers! 🧵👇

We are very excited to share our story published in Mol Syst Biol in collaboration with the Loizou Lab Joanna Loizou, describing the role of PRDX1 as a nuclear-imported antioxidant enzyme for ROS scavenging after DNA-damage 🎉🎉🎉. embopress.org/doi/full/10.15…

🔬 Targeted Protein Degradation: A new adapter molecule expands the therapeutic potential around the cell's waste disposal system, CeMM PI @georg_e_winter's team published a new study in Nature Communications : go.nature.com/3zn9Ia2 Read more ➡️ bit.ly/4cmwYn6

Beautiful work, crucial for uncovering the mechanism of alkylamine degraders, helping the progress of our recently published work. Our complementary studies together with the new FBXO22-based PROTACs from Zhang lab (nature.com/articles/s4158…) have unclocked FBXO22 for TPD!

📄 EFMC Literature Spotlight 📌 Discover our July literature spotlight; “Alkylamine-tethered molecules recruit FBXO22 for targeted protein degradation” by Winter G.E et al. 🔗 Read more: nature.com/articles/s4146… #efmcliteraturespotlight #medchem #chembio #naturepublishing