Another step toward replacing Matrigel? Excited to see this paper published! nature.com/articles/s4156… Great work by PhD students antonius chrisnandy & Delphine Blondel👏 Thanks to co-authors Saba Rezakhani Nicolas Broguiere & support from NCCR Bio-Inspired Materials & EPFL Life Sciences #LowonMatrigelhighonPEG

Cool! ukbiobank.ac.uk/learn-more-abo…

Nice coverage by Christine Weber Nature Cell Biology on our work with Jason Spence Treutlein lab exploring human endoderm development with #scRNAseq #organoids Human Cell Atlas Organoid Cell Atlas. nature.com/articles/s4155…

Now online! Deciphering cell signaling networks with massively multiplexed biosensor barcoding dlvr.it/SDLh53

Excited to finally share this amazing and highly collaborative work from our lab led by former grad student ⁦@eicheralex⁩ that models a 3-germ layer stomach model in vitro. sciencedirect.com/science/articl…

Awesome! Big congratulations to Gray Camp !

[1/n] Our new manuscript is out today in Cell! Read the details here! cell.com/cell/fulltext/…

Proteins and mRNAs do not always correlate - Check out our new paper in Nature Metabolism to see how this happens in the gut: Spatial discordances between mRNAs and proteins in the intestinal epithelium. nature.com/articles/s4225…. 1/8

Happy to share our spatial analysis of human organoids! Fun to "see" organoid structure and cell types develop with multiplexed imaging + single-cell genomics! Great collab with Gray Camp Lucas Pelkmans! Step towards virtual #Organoids, and exciting tools for phenotyping! 1/2

Super excited to host Craig Lowe from DukeMGM in Basel at the Biozentrum, University of Basel! Come learn about genetics of adaptation, iconic traits, and what makes us human! vertgenlab.org/index.html D-BSSE, ETH Zurich FMI science University of Basel

I am thrilled to share our preprint describing the development and in vitro generation of brown fat! Big thanks to ever encouraging @PourquieOlivier, all our collaborators and lovely lab members for their support!!

Huge congrats to UMCDB PhD student Renee Conway Hein and team (Joshua Wu @tristanfrum Alyssa J Miller, PhD and collaborators)! R-SPONDIN2+ mesenchymal cells form the bud tip progenitor niche during human lung development, in Developmental Cell cell.com/developmental-… #organoids

cellpypes - cell type pipes for R. Annotate scRNAseq data manually with simple rules:

Changing title and going all in for #EMBODevTempo. Exploring Human EvoDevoSpaceTime with organoid technologies! EMBL Barcelona #organoid #evodevo #singlecell embl.org/about/info/cou…. Super cool event!

It will be an extreme pleasure and honour to host the SCG 2023 at its 10th anniversary in Switzerland!!! And thanks to Alexander van Oudenaarden for an amazing meeting #SCG2022

How are cell fates in brains regulated? 🤔 An article tackling that question by ETH Zürich scientists is taking bronze in our 2022 countdown. Wohoo! 🎊 x.com/organoidscienc…

What makes our cells human? The evolution of human development is undeniably fascinating. It is an exciting time to explore the details! We, Alex Pollen, craiglowe, Umut Kılık, Nature Reviews Genetics review and suggest new inroads: rdcu.be/c4Pno #sapiens #evodevo #organoids

Save the date! Single Cell Genomics 2023 #SCG2023 takes place Oct. 9-11 2023 in the beautiful mountain town Engelberg in Switzerland! 10th year anniversary of this unique experience. IdoAmitLab, Sten Linnarsson, Alexander van Oudenaarden, MarioniLab, Rickard Sandberg, Aviv Regev, Amos Tanay

A new collaboration between ETH Zurich and Roche trains doctoral students and postdocs in bio-engineered #TranslationalMedicine in Basel. The call for applicants for the doctoral programme is open now > next-gen-bioengineers.ethz.ch. Please RT!

1/2 🚀 Discrete Optimal Transport (OT) has proved useful in a wide variety of tasks in single-cell genomics, see e.g. moscot-tools.org. Can we combine this powerful concept this with novel generative models? 🤔 🌟 Enter GENOT: Generative Entropic Neural OT.