Happy to see our review out now in Nature Reviews Cancer was fun to co-create this piece with Matthias Valentina and Georg. we aimed to be as contemporary in coverage and forward-looking in outlook on protein degraders mechanisms and cancer therapeutics. nature.com/articles/s4156…

It was great to catch up with Karen Vousden (Vousden Lab) from the #CancerGrandChallenges Scientific Committee at our #AACR2025 stand today (2327). Karen was recently awarded the AACR-G.H.A. Clowes Award for Outstanding Basic Cancer Research. Congratulations Karen! 🎉

Today at #AACR2025 Tobias Janowitz (Tobias Janowitz Cold Spring Harbor Laboratory) - co-team lead of #CancerGrandChallenges team CANCAN - gave an exciting overview of his pioneering work linking neuroendocrine and tumour-derived signals to neuropsychiatric symptoms in cancer-associated cachexia.

🎉 Huge congratulations to Karen Vousden (The Crick, and member of our Cancer Grand Challenges Scientific Committee), on receiving the prestigious AACR G.H.A. Clowes Award! Her award lecture brilliantly showcased her work in tumour suppressor biology and cancer metabolism. 👏

New perspective in Science Magazine from Gary W Miller of team SAMBAI on exposomics ⤵️ "Life exists at the interface of genetically encoded processes and environmentally driven realities. So too should the biomedical enterprise that studies it." science.org/doi/10.1126/sc…

ICYMI: Future leaders and co-first authors Marcos Díaz-Gay CNIO Stop Cancer and Sarah Moody Wellcome Sanger Institute take us through team Mutographs nature paper which indicates microbial exposure early in life may influence colorectal cancer formation decades later🔽 cancergrandchallenges.org/news/global-ch…

New review from Georg Winter and Alessio Ciulli in Nature Reviews Cancer 👇 As part of team KOODAC, Georg and Alessio are leveraging targeted degradation approaches to tackle our solid tumours in children challenge.

New review from Mariam Jamal-Hanjani (pictured below at our #AACR2025 stand 2327) and team CANCAN in Cancer Discovery 🔽 Tobias Janowitz Marcus Goncalves Eileen P. White, PhD

🌟 Hello from #AACR25 🌟It’s been a busy time at the #CancerGrandChallenges booth — great to see so many team and Committee members drop by! We’re into the final hours of AACR, so don’t miss your chance to swing by booth 2327 to learn more about our 7 new challenges!💬💡

That’s a wrap for #AACR25! What an incredible few days of meeting fellow researchers and hearing about their progress and innovations in #CancerResearch. A big thank you to AACR for hosting and to everyone who came by and spoke with us. See you next time 👋

Earlier at #AACR2025, it was fantastic to see Melissa Davis Melissa B Davis, PhD Morehouse School of Medicine, who leads #CancerGrandChallenges team SAMBAI, share the pioneering work her team is developing to understand and address cancer health inequities in populations of African descent around the world.

💡 ecDNA Conference 🗓️ 11–13 June 2025 📍 London, UK The full programme for our conference on ecDNA is now confirmed! You can view all the details and register here: bit.ly/ecDNAConferenc…

Want to share your research with the editors shaping cancer science? Join the ecDNA conference and connect with scientific editors from leading journals including nature, Cell, Cancer Discovery, and Nature Genetics. Register by 5 May: bit.ly/ecDNAConference

One day until registration closes for our ecDNA conference ⏰ Secure your spot now: bit.ly/ecDNA2025

🚨 Final call to register for our ecDNA conference this June! Registration will close tonight. Learn more: bit.ly/ecDNA2025

🎉 Huge congratulations to Prof. Cath Bollard, co-lead of #CancerGrandChallenges team NexTGen, on her appointment as Senior Vice President and Chief Research Officer at Children's National Hospital 🏥! We’re proud to have such an outstanding leader in our community. 👏✨

🧠 How do tumours and the nervous system talk—and to what end? This question drives one of 7 open #CancerGrandChallenges. Our team explores it in a new Neuron perspective. 📖 Read the full article:bit.ly/42MpdVh 📅 EOIs open until 18 June

In Discover, Charles Swanton reflects on a transformative year for #CancerGrandChallenges and shares why tackling cancer as a systemic disease is key to progress. EOIs are now open for seven new challenges. 📅 Deadline: 18 June 🔗 bit.ly/430BTqw #CancerResearch