🔥The 9th Round of Easy Loan, Earn $40 Reward is in progress❗️ ⏰ Promotion Period: January 15th - Feburary 15th, 2025 👉 Register now and check more details at gate.io/campaigns/358

Adaptive multi-epitope targeting and avidity-enhanced nanobody platform for ultrapotent, durable antiviral therapy Cell cell.com/cell/fulltext/…

@Andi_Microscopy and I structurally characterized beta cell cilia by #vEM and #UExM. It's out today in Nature Communications! We describe axoneme ultrastructural organization, as well as some novel physical contact between beta cell cilia and neurons. Link below! nature.com/articles/s4146…

CryoSTAR is officially published in Nature Methods! Huge thanks to our reviewers for their valuable feedback. In this final version, we show that an AlphaFold-predicted atomic model may serve as the reference, showcasing cryoSTAR’s flexibility. nature.com/articles/s4159…

Phylogenetic evidence supporting the nonenveloped nature of hepadnavirus ancestors | PNAS pnas.org/doi/10.1073/pn…

Florian Krammer review on antibody responses to influenza (2019). Found this review *really* well written - it flows smoothly & text is remarkable "free standing" despite copiious referencing: a tribute to author's deep personal knowledge! nature.com/articles/s4157…

TomoScore: A Neural Network Approach for Quality Assessment of Cellular cryo-ET biorxiv.org/content/10.110…

Our new preprint is out: we solved the structures of HIV-1 matrix (MA) from intact virions by SPA. The structure led us to a surprising discovery resolving a long mystery in HIV-1 biology – peptide SP2 regulates the maturation of the HIV-1 matrix. 🧵1/x tinyurl.com/c7szhtfa

I am very skeptical of the AI/ML/computational methods to predict protein-protein interactions. Prove me wrong. I present a challenge for anyone who claims they can predict protein-protein interactions. 1/n

A new Science study reports how #COVID19 travel restrictions and social measures reshaped the global dispersal of influenza. Learn more ⬇️ 📄: bit.ly/3YZ1Vd5 #SciencePerspective: bit.ly/3YWzfkB

The Master of inflenza A nucleoprotein again in action... paper coming soon!!! Congrats Florian Chenavier !!! and many thanks to the Institut de Biologie Structurale EM plateform run by @SchoehnGuy

Hepatitis B and D virus entry Watashi et al. explore hepatitis B and D virus entry, focusing on the early phase driven by viral surface antigens & related host factors, highlight the role of viral entry in tropism & discuss potential drug development targeting this process

Yesterday I had the pleasure in taking part in Nipah Day at the Pandemic Sciences Institute whereby I presented a talk on my current project: Screening of FDA-approved Compounds Using a Recombinant Cedar virus to Improve Nipah Treatment Options. Carroll Lab Gates Foundation #nipah #cedar 💊🦠

Molecular sociology of virus-induced cellular condensates supporting reovirus assembly and replication nature.com/articles/s4146…

Looking for a primer on why the contrast transfer function matters in #cryoEM? Have a look at our updated #CryoSPARC Guide pages on CTF estimation! We cover intuition, theory, job types and practical considerations: guide.cryosparc.com/processing-dat…

This year I have two projects available through the BBSRC-MIBTP at Warwick. Both focus on investigating the viral lifecycle of important RNA viruses. Please get in touch if you'd like to hear more. warwick.ac.uk/fac/cross_fac/…

Are you thinking of starting work on influenza for the first time because of... reasons? Or does your lab train people to work on flu? With Maria Amorim and Yohei Yamauchi, we've written a chapter specifically on getting up to speed on flu ... (1/2) link.springer.com/protocol/10.10…

The February issue is available! tinyurl.com/3t4hk7wa The cover highlights TomoCPT, a transformer-based solution that reformulates particle detection in cryo-ET as a centroid-prediction task using Gaussian labels. tinyurl.com/45w6cwvp

Negative Strand RNA Virus meeting #NSV2025 registration is now open! Visit negativestrandvirus.org/home

#NSV2025 Two weeks left to register! The abstract submission/registration system on the website will CLOSE Friday, April 11, 2025. Visit negativestrandvirus.org/home

Deltaviruses spread through a viral Trojan Horse biorxiv.org/content/10.110… #biorxiv_micrbio