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Higher skeletal muscle mitochondrial oxidative capacity is associated with preserved brain structure up to over a decade nature.com/articles/s4146…

✨À (re)lire! Le professeur Gilles Gouspillou et son équipe révèlent dans une étude qu’une heure d’activité physique par jour suffit à annuler les impacts négatifs de l’alitement sur la santé des personnes âgées. #UQAM Recherche et création UQAM Faculté des sciences de l’UQAM actualites.uqam.ca/2024/activite-…

How does ageing impact type I and type II myofibre properties in human muscle? Oscar Horwath, PhD, Marcus Moberg, PhD, Sebastian Edman, William Apró, PhD (gihsweden) and Andrew Philp (Centenary Institute) investigate. 📜buff.ly/40tFBJG

Excited to share our latest paper, out in Cell Reports Medicine, investigating the impact of physical activity on physical function, mitochondrial energetics, ROS production, and Ca2+ handling across the adult lifespan in men. Spearheaded by Cefis Marina & Vincent Marcangeli cell.com/cell-reports-m…

When studying mitochondria, it is essential to consider the impact of physical activity. Some findings attributed to 'aging' might actually be the result of decades of physical inactivity. cell.com/cell-reports-m…

"Lactate is NOT a metabolic waste product or the cause of muscle fatigue. Rather, it’s an intermediary and an energy source in the complex dance of metabolism. physiologicallyspeaking.com/p/physiology-f… Brady Holmer

NEWS&VIEWS | João Victor Esteves and Kristin Stanford (The Ohio State University Wexner Medical Center) The authors discuss the two studies highlighting the dual role of a novel #myokine, #Feimin, in regulating #metabolism and #exercise💪🐭👥 Read it here: rdcu.be/d76RX

Does the lack of correlation between PGC1a RNA and protein give you a headache? Us too. Phillip Dumesic has uncovered a key factor controlling PGC1a mRNA translation authors.elsevier.com/a/1kdIZ5WXUlaX…

Exercise increases brain-derived neurotrophic factor - crucial for neuronal survival, growth, and plasticity. 🧵1/9

A BIG STUDY in Nature Medicine: Which food makes you age faster? Scientists looked at 105,000 people in 30 years. The statistics is impressive. The study is open-access, so everyone can read it. 📍 Findings: The diet that ROCKS: fruits, vegetables, whole grains, unsaturated

If you're using AAVs to develop a gene therapy or to study gene function in skeletal muscle, then this may be of interest to you. In our latest work, we show that AAVs commonly used to deliver transgenes to muscle fibers also target mononuclear cells: cell.com/molecular-ther…

👋Un sujet de thèse est dispo au sein de notre équipe, dans le laboratoire CAPS de l'Unité INSERM1093, à Dijon. 🔬 «Le dialogue muscle-cerveau et le rôle des myokines dans l'amélioration de la santé cérébrovasculaire. » 🧠🏃🏃‍♀️💪

NOR-1 Overexpression Elevates Myoglobin Expression via PERM1 and Enhances Mitochondrial Function and Endurance in Skeletal Muscles of Aged Mice faseb.onlinelibrary.wiley.com/doi/10.1096/fj…

The geroprotectors trametinib and rapamycin combine additively to extend mouse healthspan and lifespan | Nature Aging nature.com/articles/s4358…

Parkin overexpression attenuates muscle atrophy and improves mitochondrial bioenergetics but fails to improve key histological features in a mouse model of Duchenne Muscular Dystrophy | bioRxiv biorxiv.org/content/10.110…