
Kristopher Sarosiek
@celldeathlab
The Sarosiek Lab @HarvardChanSPH studies the regulation of #apoptosis in human development and diseases.
ID: 872281423037771777
http://sarosieklab.org 07-06-2017 02:37:52
685 Tweet
1,1K Followers
549 Following

Thrilled to share our findings on NINJ1 autoinhibition, now online in nature. Big thanks to the amazing team Vishva Dixit Melissa Truong Matt Johnson Alexis Rohou and many others. Video by the talented, twitterless Sergei Pourmal (1/3)


Hugues de The and I want to remind you that nothing has cured more cancer patients than conventional chemotherapy!!! Think you understand how it selectively kills cancer cells so well? Take a look inside. Dana-Farber Dana-Farber News

➡️Join our next BCDI meeting for not-to-be-missed discussions on harnessing GSDMD-mediated cell death in cancer immunotherapy from Prof. Hao Wu and neutrophil-derived vesicles from Hongbo Lou's lab. Monday Jan 6th at 3PM on the Harvard Med Quad. BostonCellDeath.org


Proud to share three papers from our lab rdcu.be/d2hUm, Anthony Letai MD PhD rdcu.be/d5rb3, and R. Bernards The Netherlands Cancer Institute rdcu.be/d5rjW all showing predictable mitochondrial control of senescent cell death, using BH3 profiling as a biomarker for senolytic therapy




Radiotherapy Immunotherapy Interactions: Determinants of Success and Failure—Ralph R. Weichselbaum addressed this topic in a keynote address at the AACR Conference on Translating Targeted Therapies in Combination with Radiotherapy. #AACRradiation25 Ralph Weichselbaum




➡️Join our next BCDI meeting for exciting discussions on Regulatory T Cell fate from Xudong Li Tufts University and modulation of Gasdermin D function in pyroptosis from lab of Hongbo Luo Boston Children's! Monday March 3rd at 3PM on the Harvard Med Quad. BostonCellDeath.org




Excited to share our latest paper! Dynamic BH3 profiling predicts ALK-TKI response in NSCLC, revealing new therapeutic combos to overcome resistance. Congratulations to Dr. Martín and to all our collaborators Universitat de Barcelona Campus Clínic UB IBEC rdcu.be/eennu

➡️Join our next BCDI meeting for exciting discussions on programmed cell removal from Mounica Vallurupalli Broad Institute and NK-mediated targeting of tumor cells from Michal Sheffer Dana-Farber! Monday April 7th at 3PM on the Harvard Med Quad. BostonCellDeath.org



From the March issue: PKN2 Is a Dependency of the Mesenchymal-like Cancer Cell State brnw.ch/21wRxs9 By Shane Killarney, Kris Wood, and colleagues Duke Pharmacology & Cancer Biology Department Duke Cancer


Great talks next week, please join us ! BIDMC Cancer Center