🔥The 9th Round of Easy Loan, Earn $40 Reward is in progress❗️ ⏰ Promotion Period: January 15th - Feburary 15th, 2025 👉 Register now and check more details at gate.io/campaigns/358

Congratulations Yohei, Takeshi, and colleagues!

In-person EMBO Laboratory Leadership Course (12/3; Tokyo) and International Symposium for Female Researchers in Chromatin Symposium (12/5; online).

Work of a Ph.D. student, Fern (Watanya Trakarnphornsombat). She monitored γ-H2AX accumulation at DNA damage sites in living cells and found different regulations by ATM and DNA-PK. biorxiv.org/content/10.110…

Work by Haruka Oda on nuclear filamentous actin in zebrafish early embryos, in collaboration with groups of Nadine Vastenhouw (Lausanne) and Shigehiro Kawashima and Motomu Kanai (Tokyo). biorxiv.org/content/10.110…

Congratulations Nadine, Ksenia, and colleagues!

Satoshi Uchino's paper was selected for one of the Year in Cell Biology 2022 articles. Congratulations!

Work by Misako Tanaka, a visiting Ph.D. candidate from Tokyo Medical and Dental University, was published. Congratulations! The role of H3K9me3 in oral squamous cell carcinoma sciencedirect.com/science/articl…

STREAMING-tag paper (with RNA polymerase II Ser5ph-specific mintbody) came out. Congratulations Hiroaki, Hiroshi O, and all collaborators! nature.com/articles/s4146…

Ph.D. work by Fern (Watanya) is now published. Congrats! Watanya Trakarnphornsombat, Hiroshi Kimura; Live-Cell Tracking of γ-H2AX Kinetics Reveals the Distinct Modes of ATM and DNA-PK in Immediate Response to DNA Damage. J Cell Sci 2023; jcs.260698. doi: doi.org/10.1242/jcs.26…

The formatted version of γ-H2AX dynamics paper by Fern (Watanya) is now available. journals.biologists.com/jcs/article-ab…

Collaborative work led by Yoichi Shinkai revealed what happens to chromatin organization when mouse cells lack both H3K9 and H3K27 methylation marks. Congratulations Kei! doi.org/10.1093/nar/gk…

Nuclear F-actin dynamics in the early embryo, in collaboration with Nadine Vastenhouw, Shige Kawashima, Motomu Kanai, and colleagues. Congratulations Haruka! journals.biologists.com/bio/article/12…

Haruka Oda at the First person interview. doi.org/10.1242/bio.05…

Our #MidweekMovie shows actin dynamics in a #zebrafish embryo from Haruka Oda, Hiroshi, et al. They find that f-actin accumulates in the nucleus of early embryos & forms patches associating with condensing chromosomes. 📖Biology Open: journals.biologists.com/bio/article/12…

A review with Hiroshi Ochiai and colleagues came out. Organization of transcription and 3D genome as revealed by live-cell i... sciencedirect.com/science/articl…

Work by Masaru Nakao, who is getting PhD, was just published. Mode of SUV420H2 heterochromatin localization through multiple HP1 binding motifs in the heterochromatic targeting module - Nakao - Genes to Cells - Wiley Online Library onlinelibrary.wiley.com/doi/full/10.11…

Work by Naoki Goto (Naoki Goto), a PhD student, about histone H3K36me2 on heterochromatin was just published, in collaboration with labs of K. Yamagata, H. Kurumizaka, and H. Nishihara. Congratulations! doi.org/10.1083/jcb.20…

Congratulations Martino and Nadine!

A preprint reporting knock-in mice expressing histone H4K20me1-mintbody, by Yuko Sato and former students, in collaboration with Jun Ueda and Kazuo Yamagata. doi.org/10.1101/2024.0…

Work on knock-in mice expressing a histone modification probe (mintbody) was published. Mouse lines were generated by Jun Ueda and Kazuo Yamagata (> 10 yrs ago) and the analysis were done by Yuko Sato, Maoko Takenoshita, and Miku Ueoka. Congratulations! doi.org/10.1007/s00418…