Charles Ishak (@charlesishak) 's Twitter Profile
Charles Ishak

@charlesishak

Assistant Professor at UT @MDAndersonNews | Repetitive elements and viral mimicry in cancer

ID: 867576025231876096

linkhttps://www.mdanderson.org/research/departments-labs-institutes/labs/ishak-laboratory.html calendar_today25-05-2017 03:00:17

241 Tweet

312 Followers

695 Following

Kathleen Helen Burns (@kathleenhburns) 's Twitter Profile Photo

Check out our latest review | LINE-1 retrotransposition and its deregulation in cancers: implications for therapeutic opportunities by Carlos Mendez-Dorantes. Our thanks to Genes & Development. genesdev.cshlp.org/content/early/…

Check out our latest review | LINE-1 retrotransposition and its deregulation in cancers: implications for therapeutic opportunities by <a href="/CarlosMendezPhD/">Carlos Mendez-Dorantes</a>.
Our thanks to <a href="/GenesDev/">Genes & Development</a>. 
  genesdev.cshlp.org/content/early/…
Joya Chandra, PhD (@joyachandraphd) 's Twitter Profile Photo

Last call for undergrads interested in epigenetics summer research at MD Anderson in 2024! Deadline is 7 days away to apply for the SPCR, one of several summer programs at MD Anderson!

Nakul Shah (@nakul2234) 's Twitter Profile Photo

🧬🚨 Our study on novel antigens induced in glioblastoma upon treatment with epigenetic therapy is out!! This study was led by joshhjang with co-first-authors Yonghao Liang and Ju-Heon Maeng, and mentored by Ting Wang and Albert H. Kim. 5 Key Takeaways: 1/5 nature.com/articles/s4158…

🧬🚨 Our study on novel antigens induced in glioblastoma upon treatment with epigenetic therapy is out!! This study was led by <a href="/joshhjang/">joshhjang</a> with co-first-authors <a href="/leung_holden/">Yonghao Liang</a> and <a href="/JuheonM/">Ju-Heon Maeng</a>, and mentored by <a href="/twang5/">Ting Wang</a> and <a href="/AlbertHKimMDPhD/">Albert H. Kim</a>.  5 Key Takeaways: 1/5
nature.com/articles/s4158…
Abhinav Jain, Ph.D. (@abhinavjain_phd) 's Twitter Profile Photo

Amazing talk by Daniel De Carvalho re: functions of #retroelements in cancers. Also learned the exciting outcomes of profiling #cfDNA methylation from liquid biopsies - their non-invasive cfMeDIP-seq assay, useful for early cancer detection, subtype profiling & therapy response.

Mayor Olivia Chow 🇨🇦 (@mayoroliviachow) 's Twitter Profile Photo

It's University Health Network Week of Gratitude—a chance to applaud the incredible work of everyone at the University Health Network, Toronto's largest hospital system. 👏👏👏 Our heartfelt thanks go out to everyone at UHN and the nurses, doctors, and staff. ❤️

It's <a href="/UHN/">University Health Network</a> Week of Gratitude—a chance to applaud the incredible work of everyone at the University Health Network, Toronto's largest hospital system. 👏👏👏

Our heartfelt thanks go out to everyone at UHN and the nurses, doctors, and staff. ❤️
Princess Margaret Cancer Centre Research (@pmresearch_uhn) 's Twitter Profile Photo

This Monday, we were thrilled to host scientists from MD Anderson Cancer Center, for the Slaight Breakthrough Forum at @thepmcf. “This collaboration with MD Anderson highlights how science is a team sport, and we can accomplish more by working together," says Dr. Aaron Schimmer.

This Monday, we were thrilled to host scientists from <a href="/MDAndersonNews/">MD Anderson Cancer Center</a>, for the Slaight Breakthrough Forum at @thepmcf.

“This collaboration with MD Anderson highlights how science is a team sport, and we can accomplish more by working together," says Dr. Aaron Schimmer.
Daniel De Carvalho (@decarvalho_lab) 's Twitter Profile Photo

Our latest paper is out: "Inhibiting EZH2 targets atypical teratoid rhabdoid tumor by triggering viral mimicry via both RNA and DNA sensing pathways" nature.com/articles/s4146…

Lewis Lab (@peterlewislab) 's Twitter Profile Photo

The HuSH complex silences retrotransposable elements. We identify HuSH2, centered on TASOR2, targeting KRAB-ZNFs and interferon genes, balancing retrotransposon silencing and immune regulation. nature.com/articles/s4146…

The HuSH complex silences retrotransposable elements. We identify HuSH2, centered on TASOR2, targeting KRAB-ZNFs and interferon genes, balancing retrotransposon silencing and immune regulation. nature.com/articles/s4146…
Carlos Mendez-Dorantes (@carlosmendezphd) 's Twitter Profile Photo

Check out our latest pre-print: we show that the LINE-1 retrotransposon is a potent source of chromosomal rearrangements and instability in addition to insertional mutagenesis using shotgun and long-read WGS. Kathleen Helen Burns Jennifer Ann Karlow biorxiv.org/content/10.110…

Charles Ishak (@charlesishak) 's Twitter Profile Photo

Thank you to Daniel De Carvalho and Sajid Marhon for their leadership on this study, and all team members who made this study possible! This study represents an exciting new direction towards understanding how dsRNAs promote tumorigenesis. We're excited to expand further!