
Charles Ishak
@charlesishak
Assistant Professor at UT @MDAndersonNews | Repetitive elements and viral mimicry in cancer
ID: 867576025231876096
https://www.mdanderson.org/research/departments-labs-institutes/labs/ishak-laboratory.html 25-05-2017 03:00:17
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Check out our latest review | LINE-1 retrotransposition and its deregulation in cancers: implications for therapeutic opportunities by Carlos Mendez-Dorantes. Our thanks to Genes & Development. genesdev.cshlp.org/content/early/…



1/Now published Genome Biology! Modeling methyl-sensitive transcription factor motifs with an expanded epigenetic alphabet. By Coby Viner Charles Ishak Nic Walker Hui Shi Marcela Sjöberg Shu Yi (Roxana) Shen David Adams Anne Ferguson-Smith Daniel De Carvalho Sarah Hainer et al! genomebiology.biomedcentral.com/articles/10.11…


Congratulations Richard Wood of MD Anderson Cancer Center, newly inducted #NASmember! #NAS161 #cancerresearch #biochemistry #genetics


What an honor and privilege to work with Dr. Sharon Dent MD Anderson Cancer Center, newly elected to National Academy of Sciences . Congratulations Sharon!!

Thank you Ovarian Cancer Research Alliance for supporting Early Career investigators and cutting-edge cancer research at MD Anderson Cancer Center and beyond!

🧬🚨 Our study on novel antigens induced in glioblastoma upon treatment with epigenetic therapy is out!! This study was led by joshhjang with co-first-authors Yonghao Liang and Ju-Heon Maeng, and mentored by Ting Wang and Albert H. Kim. 5 Key Takeaways: 1/5 nature.com/articles/s4158…


Join us at the MD Anderson Cancer Center EMC seminar today at 11am as we welcome Daniel De Carvalho ! Room 4SCR1.1110. See you there!

Amazing talk by Daniel De Carvalho re: functions of #retroelements in cancers. Also learned the exciting outcomes of profiling #cfDNA methylation from liquid biopsies - their non-invasive cfMeDIP-seq assay, useful for early cancer detection, subtype profiling & therapy response.

It's University Health Network Week of Gratitude—a chance to applaud the incredible work of everyone at the University Health Network, Toronto's largest hospital system. 👏👏👏 Our heartfelt thanks go out to everyone at UHN and the nurses, doctors, and staff. ❤️


This Monday, we were thrilled to host scientists from MD Anderson Cancer Center, for the Slaight Breakthrough Forum at @thepmcf. “This collaboration with MD Anderson highlights how science is a team sport, and we can accomplish more by working together," says Dr. Aaron Schimmer.




Check out our latest pre-print: we show that the LINE-1 retrotransposon is a potent source of chromosomal rearrangements and instability in addition to insertional mutagenesis using shotgun and long-read WGS. Kathleen Helen Burns Jennifer Ann Karlow biorxiv.org/content/10.110…

Thank you to Daniel De Carvalho and Sajid Marhon for their leadership on this study, and all team members who made this study possible! This study represents an exciting new direction towards understanding how dsRNAs promote tumorigenesis. We're excited to expand further!