Congrats to my wonderful labmate, Ella, whose work demonstrating the impact genotyping error has on PGS is out today! sciencedirect.com/science/articl…

?? happy to hear this company finds that measuring gene expression via RNA is better than DNA, will definitely be giving them my $200 a month!

“The Iranian regime will, one day, fall. And when it does, women and men will regain their lives and their freedoms.” The Lancet #WomanLifeFreedom #زن_زندگى_آزادى‌

Excited that our flagship analysis of the Mexican Biobanks is now out in nature nature.com/articles/s4158…

The only time I’ve been called Dr since getting my PhD has been the place I order pizza from in a promotional marketing gimmick

so happy to see our work out in AJHG! 😊 a great collaboration during my PhD in Roel Ophoff’s lab, working with Tommer Schwarz Bogdan Pasaniuc @kangchenghou Christa Caggiano (and many others not on twitter) check it out!👇

Nothing makes me as uneasy as a human geneticist as seeing the proliferation of direct to consumer polygenic risk score companies. I know academics are conservative but these scores are truly not good enough yet & have potential for true harms

I noticed ppl disregarding the NYMag piece bc it focused on Huberman’s personal life, not bad science & harmful misinformation he propagates. So I wrote a thing. @slate: “So, Should You Trust Andrew Huberman?” slate.com/technology/202…

Really wonderful work on how our genomes might interact with commonly prescribed medications

Our paper looking at cell-free DNA epigenetic features in ALS is now out in MedRxiv! I am extraordinarily grateful for the ALS patients who participated in the study. This research would not be possible without them medrxiv.org/content/10.110…

So happy to have been at the beautiful UPitt for the inaugural #statgen2024. Super fun conference with lots of cool stat gen methods, definitely a new fave

How do quantities of brain cells – the fundamental unit of life – differ in Alzheimer’s disease, schizophrenia and autism? Our work on cell-type proportion shifts using methylomics is just out in Science Advances #PsychENCODE Michael Gandal Daniel Vo science.org/doi/10.1126/sc… 🧵

Check out our new toolkit for cell type deconvolution from DNA methylation sequencing. Open-source and ready to use! Congrats to Irene Unterman who worked tirelessly on this & thanks to Christa Caggiano and Noah Zaitlen who inspired us with the CelFiE approach. genomebiology.biomedcentral.com/articles/10.11…

Hi academic friends! Does anyone have a recent-ish NIH F32 that they would be willing to share? I can’t find any online written within 10 years, but I’d be super appreciative if anyone has an example 🙂

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A powerful alternative to principal components (PC) to account for population structure in genetic association analysis: spectral components (SPc) Compared to PC, SPc - explain more variation in population structure with fewer components (90% for SPc vs 50% for PC) - more

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