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Happy to share our recent Circulation Research podcast👇Unispital_USZ Cardiology USZ CTEC - Zurich University Heart Center Era Gorica Natalia Atzemian Ludovica Di Venanzio Marialucia Telesca Soheil Saeedi Nazha Hamdani

Our work has been selected for the May @circres Podcast! Listen the interview with Francesco Paneni and #SarahCostantino about the role of chromatin remodeling in #HFpEF Marialucia Telesca Shafeeq mohammed Era Gorica Natalia Atzemian Ludovica Di Venanzio Alessia Mongelli Nazha Hamdani

Costantino et al found that metabolic stress leads to #chromatin modifications promoting #lipid accumulation and cardiac damage in #HFpEF. Learn more at ahajrnls.org/4mkNfOV @Nazha Hamdani Omer Dzemali Era Gorica Marialucia Telesca RaffaellaSantoroLab

Zhakeer & colleagues found that the #NLRC3-#IL18 axis in Treg cells links immune dysregulation to #EndMT, providing mechanistic insights into #PH-LHD pathogenesis. Learn more at ahajrnls.org/45cyrf1

Kaoy et al found #HMGCS2 mediates the therapeutic effects of #NAD+ therapy in #HFpEF by restoring normal lipid metabolism & improving mitochondrial function in the heart. ahajrnls.org/4k2nj9b Yen Chin Koay John O'Sullivan Ashish Misra Chenchenwenwen

Methawasin & colleagues found reducing harmful protein clumps in heart muscle cells with a special molecule called antisense oligonucleotide (#ASO) could help treat #RBM20 cardiomyopathy. Learn more at ahajrnls.org/4k54X7v

ICYMI: the latest episode of Discover CircRes podcast is out, and you can listen here: bit.ly/4kr65SR

📣Calling all #AHFTC Fellows! Circ: Heart Failure is proud to launch a free educational webinar series for current or past AHFTC fellows. 📍8 live virtual sessions, 1 in-person event 📍New topic each session 📅Start Date: August 13, 2025 🔗Learn More: ahajournals.org/circheartfailu…

ICYMI: the latest episode of Discover CircRes podcast is out, and you can listen here: bit.ly/4kr65SR

Zhang & colleagues found a new mechanism where the #KLF15/VASN axis controls #Notch1 signaling to regulate #ngiogenesis. Learn more at ahajrnls.org/445hz92

📢 Expedited Review for #ESCCongress 2025! CircImaging invites authors with accepted ESC presentations to submit manuscripts for rapid review. Initial decisions within 10 days! Submit by June 23 👉 ahajournals.org/circimaging/ex… #CardioTwitter #CardioImaging Kaz Negishi@Cardiologist/ Heart Mafia

He et al found that #NEP, secreted by trophoblast cells & shuttled to maternal blood vessels through #EVs, is a key culprit behind #pre-eclampsia. Learn more about new research strategies for treating preeclampsia at ahajrnls.org/45QA9mC @mark_D_kilby

📢Expedited Review for #ESCCongress 2025! Circ: Heart Failure invites authors with accepted ESC presentations to submit manuscripts for rapid review. 📍Initial decisions within 10 days! 📝Submit by June 23 🔗Learn More: ahajournals.org/circheartfailu… #AHAJournals Nancy Sweitzer MDPhD James Fang

Check out the latest review in the June 6th issue of Circulation Research by Orlowski & colleagues "Intracellular #pH Regulation in Ventricular Myocytes: Implications for #Cardiac Health and Disease" at ahajrnls.org/4kaf2zv

Cai & colleagues developed a humanized aortic valve calcification (#AVC) model for studying valve disease. Learn more at ahajrnls.org/3SXFr8u Dunpeng Cai