🔥The 9th Round of Easy Loan, Earn $40 Reward is in progress❗️ ⏰ Promotion Period: January 15th - Feburary 15th, 2025 👉 Register now and check more details at gate.io/campaigns/358

Single Cell Genomics course in Latin America! Wet-lab part successfully completed ✅ We learnt a lot! Thanks Lia Chappell @AnitaScoonesPGR David Adams Alice Matimba Wellcome Connecting Science Learning and Training Patricia Severino Dani and Flávia (twitterless)

🎉 Our latest work demonstrating a role for macroH2A in shaping melanoma TME through its ability to dampen inflammatory 🔥 gene expression in cancer-associated fibroblasts, is out now in Nature Cell Biology!!! 🍾 Openly accessible at nature.com/articles/s4155… A thread below 👇 (1/6)

Dr. Claudia Capparelli (Claudia Capparelli) of Thomas Jefferson University and colleagues show that cIAP2 is sufficient to induce tolerance to MEK inhibitors, likely by decreasing the levels of cell death in SOX10-deficient drug tolerant persister #melanoma cells. 📑 bit.ly/3ErqN1I

Check out our latest opinion piece on stress granules as a hormetic adaptive response in cancer! Trends in Cancer @EldaGrabocka So grateful for the support of my T32 & TJU Department of Surgery Aplin Lab - Cancer Research Lucia Languino Hien Dang, PhD Charles J. Yeo, MD, FACS National Cancer Institute 👇🏼👇🏼 nam12.safelinks.protection.outlook.com/?url=https%3A%…

In just 6 weeks, the International Congress of the Society for Melanoma Research returns home to Philadelphia for its 20th anniversary!🎊In preparation, Meenhard, an original founder of SMR, shares his thoughts on the past 20 years of #melanomaresearch. tinyurl.com/ytjvk5h9

Great post about targeting Hippo/YAP-TEAD in uveal melanoma. Poster 114 #smr2023

Check it out this beautiful poster about targeting YAP-TAZ-TEAD in drug tolerant cutaneous melanoma. Poster 39 #smr2023

Signe ⁦Jefferson Research⁩ speaking on TGM2 and drug tolerant persisters in melanoma #SMR2023. Great talk.

Amazing time with the lab and the melanoma research community at this year’s SMR Society For Melanoma Research. So grateful to be a part of this field and have such incredible people as colleagues! Had so much fun at the gala and Aplin Lab - Cancer Research got us all out on the dance floor! #SMR23

I am thrilled to be named American Cancer Society Research Professor! So grateful to American Cancer Society for this honor, recognizing our team’s efforts to prevent and treat cancer. Looking forward to delivering our discoveries to all patients and communities! UC San Diego Health Moores Cancer Center

Check out our latest paper where we report the first therapy resistance mechanism leveraged by #AcralMelanoma cells to CDK4/6 inhibitors led by Kas Jagirdar, Marie Portuallo and the rest of our lab, out today in Oncogene rdcu.be/ds6xv

I am recruiting a PhD candidate (start date: 2024, ECU Joondalup campus). Please send me your interest here or to [email protected].

Fox Chase Cancer Center’s Edna “Eti” Cukierman Named to Newly Created Marvin & Concetta Greenberg Chair in Pancreatic Cancer Research Fox Chase Cancer Center onclive.com/view/fox-chase…

We celebrate the 20th anniversary of our lab with a paper just out in the 50th anniversary special issue of Cell A great way to start 2024! A TCF4-dependent gene regulatory network confers resistance to immunotherapy in melanoma: Cell cell.com/cell/fulltext/…

After long, hard, and very collaborative work, we can finally see its results published! It’s a joyful entry to the New Year! I hope that uncovering little pieces of the puzzle will eventually lead us to a holistic understanding of the complexity of melanoma…

New research examining SOX10 expression in #melanoma from Aplin Lab - Cancer Research, Claudia Capparelli, & colleagues in the latest issue of Molecular Cancer Research

Signe Caksa ⁦Jefferson Research⁩ defending her PhD thesis today and responding to questions like a ‘seasoned and experienced investigator’. Congratulations Signe! Also, wonderful to have so many of your family and friends attending.

Thanks to all the attendees for the joint lab retreat of GutkindLab, @JAguirreGhiso, Aplin Lab - Cancer Research with Claudia Capparelli Hartsough Lab and Hangauer lab. Great trainee engagement, lots of collaborative ideas and sharing of technical advice. Looking forward to next steps.

We have reached the end of the talks at the Society For Melanoma Research #TraineeMeeting! Last but not least, Jackie Flynn from Claudia Capparelli's group Thomas Jefferson University tells us about the role of the #extracellular matrix in anti-tumour immunity in drug-tolerant #melanoma

🚨We’re Hiring (✨ Please RT) We are looking for a motivated #Bioinformatician to join our lab Université libre de Bruxelles. 🎯Explore metastasis mechanisms combining mouse genetics & human biopsies. 2-year contract funded by F.R.S.-FNRS 👉 More info & apply: cwfront.ulb.ac.be/greffe/modules…