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𝗔𝗽𝗽𝗹𝘆 𝗯𝗲𝗳𝗼𝗿𝗲 𝗝𝗮𝗻𝘂𝗮𝗿𝘆 𝟯𝟭 if you want to start an independent Research Group within an excellent cardiometabolic research environment in the heart of Copenhagen! 🧑‍🔬🚀

A timely status on GPR75 👇 Will the obesity-protective properties of this receptor be translated into a drug for treating adiposity and cardiometabolic diseases? cell.com/trends/cell-bi…

Looking to relocate to Europe? CBMR is looking for three new Group Leaders to lead independent research groups in beautiful Copenhagen 🌟 Apply before January 31!

On #WorldObesityDay, we have contributed a SnapShot to a special Issue on Obesity in Cell Metabolism covering brain actions of the current and emerging weight loss drugs. Jonas Odgaard Petersen Valdemar Brimnes Ingemann Johansen UCPH Healthscience Free access link: authors.elsevier.com/a/1kiaA5WXUlaX…

On #WorldObesityDay 2025 we present a special focus issue: "Decoding the complex systems of obesity”. We explore organ cooperation, metabolic health & environmental factors like diet in obesity. Read more: hubs.li/Q039cX_H0

Just out in Cell Reports Medicine Our latest study on how glucoregulatory hormones, insulin and glucagon, regulate the ghrelin receptor antagonist LEAP2. A superb collaboration led by Valdemar Brimnes Ingemann Johansen alongside Novo Nordisk, Gentofte Hospital, and Steno Diabetes Center. cell.com/cell-reports-m…

Lowering dietary protein requires a higher total energy intake to maintain body weight in young men. New fuel for diet debates: low-protein, high-carb diets… Happy to have contributed to this fascinating paper from the Twitterless Kiens Group nature.com/articles/s4225…

🌟 Exciting News! 🌟 I am thrilled to share that my first paper as the first author, Food insecurity promotes adiposity in mice, is now published in #ObesityJournal The Obesity Society onlinelibrary.wiley.com/doi/full/10.10… #Foodinsecurity #Obesity #PhD 1/9🧵👇

REVIEW | A Vear, MT Heneka and Christoffer Clemmensen (NNF Center for Basic Metabolic Research (CBMR), UMass Chan Medical School) This Review summarizes preclinical and clinical evidence highlighting the potential of #incretin-based drugs as treatments of #neurodegenerative diseases. nature.com/articles/s4225…

GLP-1 receptors are found in key brain regions tied to neurodegenerative diseases—hippocampus, brainstem (locus coeruleus), thalamus, amygdala, and cingulate cortex. Their widespread presence suggests therapeutic potential for Alzheimer’s, Parkinson’s, and progressive

Personalized molecular signatures of insulin resistance and type 2 diabetes. Great collaboration with Anna Krook & atul deshmukh and teams! A comprehensive clinically focused study of insulin signaling in skeletal muscle. 💪 Online Cell sciencedirect.com/science/articl…

Just out in Nature Neuroscience We have identified a brain circuit that drives safety-seeking behavior, overriding essential needs like feeding. Amazing collaboration with Ole Kiehn, brilliantly led by the now Twitterless Nathalie Krauth. nature.com/articles/s4159…

How Incretin Mimetics Protect the Brain: GLP-1R agonists & GLP-1R–GIPR coagonists cross the BBB partially, reaching brainstem/hypothalamus via circumventricular organs (CVOs) or pericyte transport. Once inside, they: 🔥 Reduce neuroinflammation (inhibit NFκB, microglial

Grateful for this support from EASD & EFSD! Our work on metabolites in the labs of Christoffer Clemmensen and Zach Gerhart-Hines at NNF Center for Basic Metabolic Research (CBMR) (CBMR) has largely been made possible by the amazing research environment at CBMR - and by many collaborators both inside and outside of CBMR!

AGENDA HIGHLIGHT Session 11 features Richard DiMarchi, Timo Müller, Poanna Tran, and Christoffer Clemmensen presenting their research on incretin hormones, and how it's changing human health. Thanks to WuXi AppTec for sponsoring! aps2025.org #Peptides2025