🔥The 9th Round of Easy Loan, Earn $40 Reward is in progress❗️ ⏰ Promotion Period: January 15th - Feburary 15th, 2025 👉 Register now and check more details at gate.io/campaigns/358

The 2004 Summer Olympics opening ceremony x.com/i/status/17748…

TP53: - Discovered 45 years ago, most cited gene all time - No therapies - 500 million people currently living will die of TP53 mutant cancers without new therapies Our Preprint: - A general strategy for TP53 missense mutant cancers (majority) with prototype small molecules

Paris is truly a beautiful city!💜 These are 10 of the most beautiful competition venues at the Paris 2024 Olympics... 1. Grand Palais (Champs-Élysées) - to host Taekwondo & Fencing

This 600-year-old painting is one of the most mysterious in history. That mirror at the back is just 3 inches wide — yet it reflects the entire room in immense detail. Look closer at it and you'll realize nothing is as it seems… (thread) 🧵

***Wet lab cancer research postdoc opportunity in the Swanton lab*** - crick.wd3.myworkdayjobs.com/External/job/L… It has been a privilege to start my research career with this group and at the Crick.🧑‍🔬

Cancer research PhD opportunities with a talented and supportive group leader. 👇🏻 I had the pleasure of working with Alex during my PhD. Please share with your networks. 🧬

Together with Charles Swanton, delighted to share that our new tool, MHC Hammer - which can detect different types of HLA disruption - mutation, loss, RNA repression and alt. splicing - is now out in #NatureGenetics and available to use…nature.com/articles/s4158…... 🧵below

Mol. Cell Biology and Immunology Lab Cancer Center Amsterdam - Amsterdam UMC Institute for Immunology and infectious Diseases Ernesto Rodríguez Lotte de Winde Febe van Maldegem Amsterdam UMC Ready for #singlecellclub Mol. Cell Biology and Immunology Lab? 😀Excited to hear from Egle Kvedaraite (Karolinska Institutet) on human mononuclear phagocytes in tissue using #scRNAseq, #flowcytometry✨ & #imaging, and Emma Colliver (The Francis Crick Institute) on the PHLEX computational toolkit for #singlecellimaging 🔬

science.org/doi/10.1126/sc… T cells receive regulatory signals from close neighbours, through ligand-receptor interactions and cytokines. Therefore we dived into the local neighbourhoods of CD8 T cells to investigate why a lung cancer model was resistant to KRAS-G12C-i + a-PD1.

"Lung cancer is one of the hardest types of cancer to treat, so working out how to harness the immune system to better target tumours is so important." Read about the new work from Megan Cole, Julian Downward, Febe van Maldegem and more ⤵️ crick.ac.uk/news-and-repor…

In our new paper just out in Science Advances we investigate mechanisms that may be limiting responses of KRAS mutant lung cancer to KRAS inhibitors and immunotherapy. science.org/doi/10.1126/sc…

Hot off the press!! 🔥 Check out our work on the origins and impact of ecDNA. This was a team effort involving multiple collaborators as one of a three part series on ecDNA in nature

1/ This is the next chapter of a story about courageous patients and their families, of multidisciplinary teamwork, and hard-fought steps forward to effective therapy for #DIPG #DMG, a universally lethal cancer of the brain and spinal cord. 🧵nature.com/articles/s4158…

Vamos, Rafa Nadal!   As you get ready to graduate from tennis, I’ve got a few things to share before I maybe get emotional.   Let’s start with the obvious: you beat me—a lot. More than I managed to beat you. You challenged me in ways no one else could. On clay, it felt like I

The human proteomic revolution proceeds with high-throughput assessment, AI analytics, correlation with health and disease, drug interactions, biomarkers cell.com/cell/fulltext/…

We are so grateful to Qian_Du for this outstanding Nature Genetics News&Views piece highlighting our recent SPRINTER work and framing it so beautifully within the literature. A truly valuable resource! 🙏 Read it here👉 doi.org/10.1038/s41588… 🧵Dive into SPRINTER's work 👇

Huge congratulations Simone Zaccaria!! So utterly well deserved. Great news to round off a wonderfully successful year. Thank you for the inspiration and mentorship you are providing to so many of us who are setting out on our cancer research careers. 🌟

It’s been a long time coming…#PhDone

Just over 2 weeks to go until my TCS London Marathon run in aid of Pancreatic Cancer UK - Last long run was 21.8 miles 🏃‍♀️- Pancreatic cancer is a cause close to my ❤️ after the death of a friend - Any donations to my fundraising page are gratefully received 🙏🏻 - 2025tcslondonmarathon.enthuse.com/pf/emma-colliv…