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Prof Rod Taylor and Dr anthony Muchai Manyara next to our poster on the new SPIRIT-and CONSORT-Surrogate extensions. If at #ictmc2024 come chat with Rod from 12:30pm on reporting surrogate endpoints, its poster number 213.#surrogateendpoints

This morning at #ICTMC2024 JAMA Editor in Chief Kirsten Bibbins-Domingo JAMA Statistical Editor Roger Lewis Marion Campbell of University of Aberdeen Kathryn Rowan ICNARC Rod Taylor University of Glasgow Provide a #JAMASummit update: Is the Clinical Trials Enterprise Broken? And How Can it be Fixed?

Our project co-lead Prof Rod Taylor will be speaking at this important spotlight session #ICTMC2024 @ictmc2024

Poster up, number 488. Come view and chat about minimum and ideal sample size in multistakeholder Delphi surveys @ictmc2024 #ICTMC2024

Finally Rod Taylor on clinical trial outcome and endpoint assesment 👇🏼

Prof Rod Taylor's presentation on clinical trial endpoint and outcomes selection in the JAMA spotlight session at @ictmc2024 #ICTMC2024

Bedside implications of the use of surrogate endpoints in solid and haematological cancers: implications for our reliance on PFS, DFS, ORR, MRD and more bmjoncology.bmj.com/content/3/1/e0… via Timothée Olivier, MD et al

📢🆕 editorial on the SPIRIT and CONSORT surrogate extensions in Journal of Dental Research Sage Journals by Falk Schwendicke and Nick Jakubovics which includes examples of surrogate endpoints in dentistry clinical trials 🔗🔗journals.sagepub.com/doi/10.1177/00…

A few weeks ago the World Health Organization (WHO) published new guidance on best practice for clinical trials. It provides really useful considerations for the design and delivery of a quality trial & the wider trials eco-system 1/6 #MethodologyMonday #101

Our next round of recruitment to our MRC TMRP DTP is now open. You can view the full list of fully funded PhD studentships available here mrctmrpdtp.com/current-opport…

Surrogate End Points in Trials—SPIRIT and CONSORT Extensions jamanetwork.com/journals/jama/…

#ictmc2024 might have been a few weeks ago now, but the learnings have stayed with us. For instance, did you know about the @LIGHTSdatabase ? This fantastic resource compiles methods guidance for a range of topics to search through! Check it out below - lights.science

Editorial from Rod Taylor, anthony Muchai Manyara, Joseph Ross, and Oriana Ciani describes the use of surrogate end points and provides new guidance for reporting studies with surrogate outcomes. #JAMASummit ja.ma/4eYIjLy

Five Q&As in 5min for better Patient, Public Involvement with health research on #PPI #Research #TrialsMethodology YouTube youtu.be/HBG6ST-yvrw

Our last output for this year is this editorial in Journal of Physiotherapy led by Christina Faria on Surrogate endpoints in trials of physiotherapy interventions 📎doi.org/10.1016/j.jphy… 📝 Janaine Polese anthony Muchai Manyara Rod Taylor Oriana Ciani Aline Alvim Scianni

A Call for Transparency, Improved Reporting and Interpretation of Trials Using Surrogate Endpoints in Cardiac Electrophysiology Larisa Tereshchenko, MD, PhD heartrhythmjournal.com/article/S1547-…

Guidelines: reporting & interpretation #RCT surrogate SPIRIT|CONSORT-SURROGATE #EPeeps Heart Rhythm Society Kenneth Ellenbogen Sumeet Chugh Sanjiv Narayan Marmar Vaseghi MD PhD Kenneth Bilchick Pasquale Santangeli Mina Chung MD Oussama Wazni Samir Kapadia Cleveland Clinic Lerner Research Institute Cleveland Clinic Heart, Vascular & Thoracic EQUATOR Network Oriana Ciani Medical Research Council SCTorg

Authors, editors, reviewers, and other potential users should use CONSORT 2025 when writing and evaluating manuscripts of randomized trials to ensure that trial reports are clear and transparent. Learn more in this Special Communication. ja.ma/4ilAvEx

NEW PAPER: Updated CONSORT-2025 for reporting randomised trials is now available in the The BMJ JAMA The Lancet Nature Medicine PLOS Medicine —> bmj.com/content/389/bm… #OpenScience #OpenAccess #transparency #medX #statsX #epiX

Happy International Clinical Trials day to all who participate, design, conduct, report, review and fund clinical trials!