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Intention-to-treat analyses may be diluted by noncompliance, while per-protocol analyses have selection bias. Instrumental variables methods may solve both problems. Angrist and colleagues discuss instrumental variables estimation in clinical trials. 👉 eviden.cc/4kLNGRM

📢 Our paper "AI safety for everyone" is out at Nature Machine Intelligence Nature Machine Intelligence . We challenge the narrative that AI safety is primarily about minimizing existential risks from AI. Why does this matter? A 🧵

...et notre réponse: thelancet.com/journals/lanps…

In The Lancet Psychiatry #ADHD Edoardo G. Ostinelli Andrea Cipriani thelancet.com/journals/lanps…

"J'ai un #TDAH, et je suis très sensible aux bruits. C'est lié?" La réponse est oui. Et on le sait grâce à cette nouvelle meta-analyse. Merci à Samuele Cortese pour sa suggestion et son travail! jaacap.org/article/S0890-…

#GRADE, indeed #EBM, will never be the same. GRADE papers have become too complex and difficult to navigate. The remedy: a series of 7 papers in the #BMJ laying out the essentials of GRADE: Core GRADE. This week, an overview of Core GRADE. bmj.com/content/389/bm…

Great to see our The Lancet Psychiatry #network #metaanalysis on the #cardiovascular effects of #ADHD medications (thelancet.com/journals/lanps…) featured in Medscape Psychiatry (medscape.com/viewarticle/ad…)

Communication about our course on #child and #adolescent #mental health out ESCAP journal link.springer.com/article/10.100… Places for the 5th edition (1–4 October 2025) in #Sicily, #Italy are still available. Please register here residentialcourse.com/5th_edition/ Luigi Mazzone

Our #metaanalysis (n = 231) in JAMA Psychiatry reveals consistent brain abnormalities across #sleep disorders involving affective and cognitive hubs in sgACC, amygdala/hippocampus Short-term sleep deprivation shows a distinct picture, affecting the thalamus jamanetwork.com/journals/jamap…

ADHD Treatment: Understanding Evidence and Practice #ACAMHlearn 'Learning Series' with Samuele Cortese University of Southampton Includes a quiz to test your knowledge and free CPD certificate when you set up an ACAMH Learn account (also free!) bit.ly/426sM7p

Registration for the 5th Residential CAP course is still open! To find out more, read the just published ESCAP Communication on the 2024 course: link.springer.com/article/10.100… For all info and to register for 2025: residentialcourse.com/5th_edition/ 1-4 Oct 2025 in Catania, Sicily/Italy

NEW PAPER: Updated SPIRIT-2025 for reporting protocols of randomised trials is now available in the The BMJ JAMA The Lancet Nature Medicine PLOS Medicine —> bmj.com/content/389/bm… #openscience #transparency #medX #statsX #epiX

Just 2 months until our congress! Have you started planning your stay yet? Join Congress President Carmen Schröder on a tour around Strasbourg: youtu.be/cV7YfTe2G0w?si… Find out more and register now: escap2025.eu #ESCAP2025

New in The BMJ: Gabapentinoid treatment not directly linked to increased self-harm risk. Risk is highest before and after treatment—not during. Close monitoring needed across the full treatment journey. Read more: bmj.com/content/389/bm…

How do we turn our public health research into real-world impact? This short video shares a quick look at some of the people who are helping NIHR make a difference in this space— watch the full story on YouTube ➡️ youtube.com/watch?v=8xMAIA….

Samuele Cortese Marco Solmi Psychology at Soton UNM Psychology

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