🔥The 9th Round of Easy Loan, Earn $40 Reward is in progress❗️ ⏰ Promotion Period: January 15th - Feburary 15th, 2025 👉 Register now and check more details at gate.io/campaigns/358

1/- Amidst tough times all round this is very exciting for us. Our first preprint - we identify and characterise factors that regulate global and focal DNA (de)methylation during developmental epigenome remodelling phases. Check the thread for a low-down: biorxiv.org/content/10.110…

It’s out!! Beautiful work from my lab on the role of Dppa2/4 in establishing a permissive epigenome during early mammalian development. Go and check it out on Nature Structural & Molecular Biology! nature.com/articles/s4159… congrats Kristjan Gretarsson and Jamie Hackett

If you love epigenetics just as much as we do, don’t miss our latest review on CRISPR-Cas9 technology and how this can be used to address many unresolved questions in the epigenetic field. Out today! Jamie Hackett EMBL Rome @JujuDabin onlinelibrary.wiley.com/doi/10.1002/bi…

📢Preprint! In what contexts can #epialleles confer heritable memory in mammals? What are the mechanisms that restrict/promote this? Find out more in our study coupling an optimised epigenetic editing system (iCRUSH), CRISPR screening & cell contexts👇 biorxiv.org/content/10.110…

FACS you, I won't do what you tell me.

Our latest study on epigenetic inheritance in pluripotent cells is now out in the current issue of the EMBO journal! Well done Valentina Carlini Jamie Hackett!!! Check out the beautiful artwork featured on the cover made by my talented colleague Marzia Munafò. dx.doi.org/10.15252/embj.…

📢Preprint drop! -Are chromatin modifications a cause or consequence of transcription? (or both) How do DNA motifs affect the function of marks? Can combinatorial modifications synergise? We present our epigenome editing study, & unexpected findings👇+🧵 biorxiv.org/content/10.110…

I am extremely thrilled and proud to announce that my work from the last five years is finally out on preprint! Epigenetic marks and transcription: - Cause vs consequence - Synergistic effects - Interaction with cis genetic motifs - unexpected results biorxiv.org/content/10.110…

🥳 We are delighted to welcome a NEW Research Group to MPI of Immunobiology & Epigenetics. The Ayele Argaw Denboba lab (Follow ➡️Ayele A.Denboba) joins Max Planck with exciting projects on #microbiome-#epigenome interactions & epigenetic inheritance. – Welcome! INTERVIEW: ie-freiburg.mpg.de/5786033/2023_0…

Proudly presenting the ten #selected #startups of this year's Startup Pitch & Partner Program at #BioVaria! Looking forward to hearing more about these exciting technologies during the Startup #Pitch Session on the first day of #BioVaria!

I am proud to announce that our #startup , Epitome Therapeutics, has been #selected to give a pitch at the next #Biovaria meeting 🥳 Looking forward to present in Munich and build new connections! ⁦Jamie Hackett⁩ ⁦EMBL Rome⁩ ⁦EMBL⁩

After more than a decade focused on genome editing of DNA, it could turn out that editing the #epigenome, which regulates gene expression, is a better, or, at the very least, a highly complementary strategy nature.com/articles/s4158… Nature Genetics Cristina Policarpi Jamie Hackett EMBL

Non più solo accendere e spegnere i singoli geni, ma ‘sintonizzare’ con precisione la loro attività: è possibile farlo ora grazie a un kit che regola l'epigenetica, ossia il sistema che come un direttore d’orchestra guida l’attività del Dna. EMBL ansa.it/canale_scienza…