
Cristina Policarpi
@cristinapolica4
Epigenetics and transcription. post-doc at EMBL Rome @hackettlab
ID: 1240240458846081036
18-03-2020 11:35:54
20 Tweet
191 Followers
42 Following

1/- Amidst tough times all round this is very exciting for us. Our first preprint - we identify and characterise factors that regulate global and focal DNA (de)methylation during developmental epigenome remodelling phases. Check the thread for a low-down: biorxiv.org/content/10.110ā¦

Itās out!! Beautiful work from my lab on the role of Dppa2/4 in establishing a permissive epigenome during early mammalian development. Go and check it out on Nature Structural & Molecular Biology! nature.com/articles/s4159⦠congrats Kristjan Gretarsson and Jamie Hackett


š¢Preprint! In what contexts can #epialleles confer heritable memory in mammals? What are the mechanisms that restrict/promote this? Find out more in our study coupling an optimised epigenetic editing system (iCRUSH), CRISPR screening & cell contextsš biorxiv.org/content/10.110ā¦


Our latest study on epigenetic inheritance in pluripotent cells is now out in the current issue of the EMBO journal! Well done Valentina Carlini Jamie Hackett!!! Check out the beautiful artwork featured on the cover made by my talented colleague Marzia Munafò. dx.doi.org/10.15252/embj.ā¦

š¢Preprint drop! -Are chromatin modifications a cause or consequence of transcription? (or both) How do DNA motifs affect the function of marks? Can combinatorial modifications synergise? We present our epigenome editing study, & unexpected findingsš+š§µ biorxiv.org/content/10.110ā¦


š„³ We are delighted to welcome a NEW Research Group to MPI of Immunobiology & Epigenetics. The Ayele Argaw Denboba lab (Follow ā”ļøAyele A.Denboba) joins Max Planck with exciting projects on #microbiome-#epigenome interactions & epigenetic inheritance. ā Welcome! INTERVIEW: ie-freiburg.mpg.de/5786033/2023_0ā¦



After more than a decade focused on genome editing of DNA, it could turn out that editing the #epigenome, which regulates gene expression, is a better, or, at the very least, a highly complementary strategy nature.com/articles/s4158⦠Nature Genetics Cristina Policarpi Jamie Hackett EMBL

