We all have an #ageing clock. Some things will make it tick faster. Some will make it slower. But can we use this knowledge to rejuvenate cells? Find out more with Diljeet Gill and Reik Lab Watch the video: ow.ly/cxjy50F6zFv Read the preprint: ow.ly/vH7M50F6zFu

High numbers of senescent cells predisposed aged mice to severe inflammation and death from infection with a relative of #SARSCoV2, possibly helping to explain why elderly and chronically ill patients are especially vulnerable to #COVID19. fcld.ly/81o8qfl #WeekendReads

Accurate inference of genome-wide spatial expression with iSpatial biorxiv.org/content/10.110…

Thank Tallulah Andrews comment. KNN-smooth is one of the best scRNA imputation methods (PMID: 32854757). The smooth is optional in our method. We have indeed assessed this step which actually reduces false positive, at least on some marker genes (see fig. S8A). biorxiv.org/content/10.110…

Check our detailed protocol for eccDNA purification. We finally solved the “Solution A” supply problem after a long discussion with the manufacture. Now, it will be sold as a single reagent to save user’s money. biorxiv.org/content/10.110…

Next Monday will start teaching a summer course on “High Dimensional Date Analysis” for Tsinghua-Berkeley Shenzhen institute, three hours a day everyday for two weeks. Three years in a row remote teaching… really miss the fresh lychee in Shenzhen.

Understanding prefrontal cortex functions by decoding its molecular, cellular and circuit organization biorxiv.org/content/10.110…

Thrilled to share this with you!🥳 A truly wonderful journey

Biology is beautiful—and Xenium proves it by bringing it to life with the new Mouse Tissue Atlasing Panel. Learn how #singlecellspatial imaging can help you uncover the splendor of your sample here: bit.ly/4835hhy