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For >20 years obesity was thought to be associated with reduced dopamine receptors in brain reward regions. Now, a big study by Valerie L. Darcey, PhD, MS, RD shows that this may be have been an artifact (top figure panel) due to brain dopamine tone being positively associated with body fat (bottom).

#ACC2025 Obesity Wrap Up: Dr. Belardo and I discuss the PRAGUE-25 trial (catheter ablation vs. antiarrhythmics with weight management and lifestyle alterations in AF), SOUL trial (oral semaglutide vs. placebo in DM with ASCVD/CKD), STRIDE trial (semaglutide vs. placebo in DM with

Sekar Kathiresan and I discuss "one and done" gene editing for high cholesterol by permanently inhibiting PCSK9 by about 70% to achieve an average LDL lowering of 59%. There were no safety signals in this early study.

After 21 years at my dream job, I’m very sad to announce my early retirement from the National Institutes of Health. My life’s work has been to scientifically study how our food environment affects what we eat, and how what we eat affects our physiology. Lately, I’ve focused on

💔 Heart breaking to loose one of the best researchers at ⁦NIH⁩ and fellow Canadian 🇨🇦 ⁦ASPC⁩ ⁦Danielle Belardo, MD⁩ nytimes.com/2025/04/16/wel… via The New York Times

Sad to hear Kevin Hall is leaving NIH, but couldn’t be more excited for what’s next. The most brilliant scientist in the world-who redefined how we understand obesity & metabolism-is officially on the market. If you’re in pharma, obesity science, venture, it’s time to snag him!

Congrats to Gurleen Kaur, MD who led our latest #MGBLpaRegistry paper showing that ⬆️Lp(a) is a/w higher rates of CVD & MI in both women and men. Our findings suggest that ⬆️Lp(a) may pose a higher relative risk in post menopausal women (vs. younger women)

High Apo B, LDL-C, incoming STEMI…Lakers in 5. shannon sharpe

This is great info! Thank you C. Michael Gibson MD and Danielle Belardo, MD for sharing!

Danielle Belardo, MD shannon sharpe 😆 🤣 Aki, UTI, no contrast for that MRI ---- Lakers in 5 🏀

Our ASPC statement on South Asians & Cardiometabolic Health in AJPC I had the honour of co-chairing this w/ the amazing Anand Rohatgi & Jaideep Thank you to our entire talented team who brought this to life 📎shorturl.at/4bJGz #CVPrev #CardioTwitter

👀 ⬇️This will be great new #ACCAthleticHeart session with Eli Friedman and Matthew W Martinez headlining!! (Sold out in person but still space to join virtually 💻)

Celebrated the one and only Dr. Martha Gulati ♥️🫀❤️‍🩹🇨🇦 birthday this weekend with my favorites! JK Han MD ❤️ we missed you Preethi Pirlamarla MD 🥰

🥩There have been **36 RCTs** testing effects of unprocessed red meat on cardiometabolic health vs. a range of control foods: 🍗🐟other meats, 🍞carb-rich foods, 🫘🫛🥦or veg/plant proteins. 23 of these comparisons were funded by meat industry...so what? nytimes.com/2025/05/20/wel…

I had the pleasure of writing this editorial for #EJPC with Lily N Dastmalchi DO, MA on Age at Menarche and Cardiovascular Risk: A Moving Target of Risk Assessment in Women Preprint now at 📎academic.oup.com/eurjpc/advance… EJPC Editor-in-Chief

Buon giorno a tutti! Che sia un'altra giornata indimenticabile! Forza Jannik! 🙏🦊💪🎾🎾🇮🇹🎾🎾🏆🎉🙏