🔥The 9th Round of Easy Loan, Earn $40 Reward is in progress❗️ ⏰ Promotion Period: January 15th - Feburary 15th, 2025 👉 Register now and check more details at gate.io/campaigns/358

Global researchers you can now access the Mexico City Prospective Study! We’re honored to partner with UNAM & Oxford Population Health (OxPop) to make this important #genetic dataset accessible for the global research community via our Trusted Research Environment. More: hubs.ly/Q03kF-BN0

STABIX: Summary statistic-based GWAS indexing and compression academic.oup.com/bioinformatics… 🧬🖥️🧪 github.com/kristen-schnei…

scACCorDiON: A clustering approach for explainable patient level cell-cell communication graph analysis academic.oup.com/bioinformatics…

Release of DeepVariant and DeepSomatic v1.9 DV: Added training on HG002 T2T-Q100. Error reduction of 12% for Illumina and 30% for PacBio on this truth set. 25% faster. DeepTrio is 5x faster (20h -> 4h). DS: New models FFPE_TUMOR_ONLY for {WGS, WES}. Much improved WGS models.

Already 30+ registered for our 7th Structural Variants, Graph genomes #bioinformatics #hackathon: fritzsedlazeck.github.io/blog/2025/hack…… Registration closes 10th of Aug! Groups will work on interesting topics that will be published in F1000. BCM HGSC From the Labs at Baylor College of Medicine Rice Computer Science

What an incredible few days! 🎉 The Nextflow Training and nf-core Hackathon have officially wrapped up. A huge thank you to all the trainers, organizers, and participants who made it possible.

Do you have an interesting benchmark experiment? We wanna hear about it! Special issue in Genome Biology live now: biomedcentral.com/collections/CO… Submission Deadline: 28 January 2026 #bioinformatic #genetic #genomics please share with your peers!

📰 Throughout May we have seen a number of interesting health research stories published featuring UK Biobank data. Take a look at this selection 🔽

Pan-cancer human brain metastases atlas at single-cell resolution cell.com/cancer-cell/ab…

The auxin response factor (ARF) gene family in the #chickpea reference genome has 24 loci, encoding up to 44 protein isoforms. 🌱🧬 With the #refseqR package, go from gene IDs ➡️ transcript IDs ➡️ fetch CDS sequences for all variants—fast & reproducible! ⚙️#RStats #bioinformatics

How can we make genomic foundation models actually useful to biology?! Teach them to REASON!! 🧬 Excited to share BioReason - the first model to successfully integrate DNA foundation models (eg, Evo 2) with LLMs (eg, Qwen3) for biological reasoning! 🔬 What we built: • Novel

GeneChat: A Multi-Modal Large Language Model for Gene Function Prediction biorxiv.org/content/10.110…

You think two genes are correlated. But what if there's a third gene pulling the strings? Let’s talk about partial correlation in bioinformatics.

Healthspan has a proteomic signature! About 3,000 plasma proteins assessed and validated in 2 cohorts. Immune response and inflammation proteins stood out. pnas.org/doi/10.1073/pn…

🧬 ChatNT lets you talk to DNA, RNA & proteins My first honest thought was “who needs that? 🤔” turns out it’s built for non-coders 🧑‍🔬 It beats specialist models on 27 tasks and resets the Nucleotide-Transformer benchmark 🏆

PhenoGraph: A Multi-Agent Framework for Phenotype-driven Discovery in Spatial Transcriptomics Data Augmented with Knowledge Graphs biorxiv.org/content/10.110…

We're very excited to reveal that we have been collaborating with the amazing team @NVIDIA to significantly accelerate Boltz-2 via new #cuEquivariance kernels and create Boltz-2 NIM for everyone to deploy! Just announced on stage at #GTCParis!

In our #chickpea breeding program, we use wild material to introgress genes of interest into the cultivated species. 🌿👨‍🔬 Alejandro Carmona Jimenez presents his study to characterize pod dehiscence (one unintended effect) using interspecific recombinant populations at #SECHVLC2025 🧬💻

🧬 From zero to enzyme in 35 designs 👀 Riff‑Diff uses diffusion to scaffold catalytic motifs, spinning out retro‑aldol & MBH biocatalysts that match lab‑evolved rates (no huge screens) It's an RFdiffusion‑powered workflow that “locks” hand‑picked catalytic arrays into de novo

GROMACS just went all‑GPU for free‑energy perturbation (FEP): 8× speed‑ups on an A100 without losing 1 kcal/mol accuracy ABFE just went from 400h → 48h