Dana-Farber Chemical Biology Program (@dfci_chembio) 's Twitter Profile
Dana-Farber Chemical Biology Program

@dfci_chembio

We use chemical creativity to tackle hard biology questions, target the “undruggable”, & train the next generation. Part of @DanaFarber research universe.

ID: 946467560664588291

linkhttps://tinyurl.com/ycft39sn calendar_today28-12-2017 19:47:05

1,1K Tweet

4,4K Followers

1,1K Following

Dana-Farber Chemical Biology Program (@dfci_chembio) 's Twitter Profile Photo

We are excited to be hosting Christopher D. Lima, PhD (Memorial Sloan Kettering Cancer Center / HHMI investigator) as a speaker in our Chemical Biology Seminar Series. Great way to kick off 2024/25 season of science and sharing!

We are excited to be hosting Christopher D. Lima, PhD (<a href="/MSKCancerCenter/">Memorial Sloan Kettering Cancer Center</a> / <a href="/HHMINEWS/">HHMI</a> investigator) as a speaker in our Chemical Biology Seminar Series. Great way to kick off 2024/25 season of science and sharing!
Stephan Hacker (inactive account) (@stephanhacker2) 's Twitter Profile Photo

Interesting talk by Samantha Bevill Dana-Farber Chemical Biology Program at #TPDWebinar. She talked about her research into developing tumor-specific PROTACs on the example of engaging the E3 ubiquitin ligase MDM2 to specifically degrade proteins in MDM2-amplified cancer cells. cell.com/cell-genomics/…

Katherine A Donovan (@kdonovan1008) 's Twitter Profile Photo

We are happy to share our new preprint bioRxiv "Unveiling the hidden interactome of CRBN molecular glues with chemoproteomics" led by Kheewoong Baek and Rebecca Metivier of Fischer Lab biorxiv.org/content/10.110…

Harvard Medical School (@harvardmed) 's Twitter Profile Photo

Next year, HMS will welcome its first class of students to a new master’s program (MMSc in Therapeutic Sciences). Preparing students for careers focused on early drug discovery that translates to new medicines has long been a core goal of the HMS Therapeutics Initiative.

MIT Jameel Clinic for AI & Health (@aihealthmit) 's Twitter Profile Photo

Hear from Nick Polizzi about how AI can optimize protein-ligand interactions at #MoML2024 on Nov. 5! Early Bird tickets are still available until Oct. 4! 🐦 Register now: moml.mit.edu

Hear from <a href="/nickpolizzi_/">Nick Polizzi</a> about how AI can optimize protein-ligand interactions at #MoML2024 on Nov. 5! Early Bird tickets are still available until Oct. 4! 
🐦 Register now: moml.mit.edu
Milka Kostić, PhD (@milkakostic) 's Twitter Profile Photo

Becoming the editor of Chemistry & Biology and relaunching it into Cell Chemical Biology (CellChemicalBiology) in 2016 were FUN! BUT: interacting with thousands of scientists from across the globe was... PRICELESS! With gratitude, Milka sciencedirect.com/science/articl…

Becoming the editor of Chemistry &amp; Biology  and relaunching it into Cell Chemical Biology (<a href="/CellChemBiol/">CellChemicalBiology</a>)  in 2016 were FUN! BUT: interacting with thousands of scientists from across the globe was... PRICELESS! 
With gratitude, Milka
sciencedirect.com/science/articl…
Hojong Yoon (@hojong_yoon) 's Twitter Profile Photo

Excited to kick off our post-summer series! This Thursday we are hosting Gopal Sapkota sharing insights on redirecting phosphatase through induced proximity. **Important: The time has changed to 12 PM EST!

Excited to kick off our post-summer series! This Thursday we are hosting <a href="/gpsapkota/">Gopal Sapkota</a> sharing insights on redirecting phosphatase through induced proximity.

**Important: The time has changed to 12 PM EST!
Jhoely Duque-Jimenez (@jduquejimenez) 's Twitter Profile Photo

Congratulations to the entire Xin Zhou Lab in collaboration with the Pasi lab on this new manuscript! Thank you Xin for letting me support this incredible project. Honored and grateful to have been a part it! #SiSePuede

Congratulations to the entire <a href="/xinzhoulab/">Xin Zhou Lab</a> in collaboration with the Pasi lab on this new manuscript! Thank you Xin for letting me support this incredible project. Honored and grateful to have been a part it! #SiSePuede
Dana-Farber Chemical Biology Program (@dfci_chembio) 's Twitter Profile Photo

Now in nature: work from Xin Zhou Lab on developing TransTACs, a new platform for degrading membrane proteins with many different applications like reversible control of CAR-T. nature.com/articles/s4158…

Xin Zhou Lab (@xinzhoulab) 's Twitter Profile Photo

We are excited to share our lab’s first research article! rdcu.be/dU5AC We have developed Transferrin Receptor Targeting Chimeras (TransTACs), a novel class of heterobispecific antibodies designed for targeted degradation of membrane proteins. nature.com/articles/s4158…

Puigserver Lab (@puigserver_lab) 's Twitter Profile Photo

New studies from our lab published in CellChemicalBiology designing anti-diabetic metabolic routes using novel small molecules (SR-18292) that re-direct lactate and gluconeogenic carbon substrates to mitochondrial oxidation cell.com/cell-chemical-…

Milka Kostić, PhD (@milkakostic) 's Twitter Profile Photo

Thanks to the wonderful team at Dana-Farber Communications, Dana-Farber Chemical Biology Program Program has a new website! I am especially proud of our Careers page that includes a link to an onboarding document for incoming techs, postdocs and students! dana-farber.org/research/integ…

Dana-Farber (@danafarber) 's Twitter Profile Photo

Xin Zhou, PhD, a researcher at Dana-Farber and her team have developed a new platform that repurposes a cancer cell's own refueling mechanism to degrade proteins driving tumor growth. This breakthrough could reshape how we approach cancer treatment. blog.dana-farber.org/insight/2024/1…

Adam Durbin (@adurbinlab) 's Twitter Profile Photo

An absolute pleasure to be able to contribute to this book with the amazing Jun Qi Lab, and brilliant Qi Liu and Aimee Qi. From Royal Society of Chemistry, “Epigenetic Drug Discovery.” We specifically focus on targeting histone acetyltransferases, and new chemical strategies to target them.

Zuzanna Kozicka (@zkozicka) 's Twitter Profile Photo

Very excited for our next seminar this Thursday: Derek Bartlett (formerly Pfizer Inc., now UNC-Chapel Hill) will share insights on PK-PD modelling for TPD and Kyle Mangano (Amgen 🧪🔬🧬) will present how VIPER-TACs co-opt viral E3s. 👉Join us at 12 PM EST/ 6 pm CET (back to original schedule)!

Very excited for our next seminar this Thursday: 
Derek Bartlett (formerly <a href="/pfizer/">Pfizer Inc.</a>, now <a href="/UNC/">UNC-Chapel Hill</a>) will share insights on PK-PD modelling for TPD and Kyle Mangano (<a href="/Amgen/">Amgen 🧪🔬🧬</a>) will present how VIPER-TACs co-opt viral E3s.
👉Join us at 12 PM EST/ 6 pm CET (back to original schedule)!
Science in Boston (@scienceinboston) 's Twitter Profile Photo

Transferrin receptor 1 is a cell receptor that pulls iron into the cell. ♻️ The Xin Zhou Lab at Dana-Farber has investigated repurposing this receptor as a protein degradation mechanism for a potential #CancerTherapy. 📃 nature go.nature.com/4fcwd19 📰 bit.ly/4ffMGBK

Transferrin receptor 1 is a cell receptor that pulls iron into the cell.

♻️ The <a href="/xinzhoulab/">Xin Zhou Lab</a> at <a href="/DanaFarber/">Dana-Farber</a> has investigated repurposing this receptor as a protein degradation mechanism for a potential #CancerTherapy.

📃 <a href="/Nature/">nature</a> go.nature.com/4fcwd19
📰 bit.ly/4ffMGBK
Target 2035 (@target2035) 's Twitter Profile Photo

🎙️ The Target 2035 podcast series is officially LIVE! In our pilot episode, meet our hosts - Milka Kostić, PhD, Rachel Harding and Opher Gileadi who share their personal motivations for joining the Target 2035 initiative. Tune in to the pilot episode now! podcasters.spotify.com/pod/show/targe… 🎧