
Dana-Farber Chemical Biology Program
@dfci_chembio
We use chemical creativity to tackle hard biology questions, target the “undruggable”, & train the next generation. Part of @DanaFarber research universe.
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https://tinyurl.com/ycft39sn 28-12-2017 19:47:05
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Interesting talk by Samantha Bevill Dana-Farber Chemical Biology Program at #TPDWebinar. She talked about her research into developing tumor-specific PROTACs on the example of engaging the E3 ubiquitin ligase MDM2 to specifically degrade proteins in MDM2-amplified cancer cells. cell.com/cell-genomics/…

We are happy to share our new preprint bioRxiv "Unveiling the hidden interactome of CRBN molecular glues with chemoproteomics" led by Kheewoong Baek and Rebecca Metivier of Fischer Lab biorxiv.org/content/10.110…

This week is postdoc appreciation week!! Thanks to all our awesome postdocs for fueling discovery in Dana-Farber Cancer Biology Department labs!! Hope you enjoy this week's events organized by DFCI Postdoctoral and Graduate Student Association


#Featured Voices: Michelle Arkin, Sara Buhrlage, Ling-Ling Chen, Peng Chen, Jason Gestwicki, Chuan He, Gerald Joyce, Angela Koehler, Milka Kostić, PhD, Jun Liu, Jim Wells on CCB and chemical biology. dlvr.it/TDRfDM

Hear from Nick Polizzi about how AI can optimize protein-ligand interactions at #MoML2024 on Nov. 5! Early Bird tickets are still available until Oct. 4! 🐦 Register now: moml.mit.edu


Becoming the editor of Chemistry & Biology and relaunching it into Cell Chemical Biology (CellChemicalBiology) in 2016 were FUN! BUT: interacting with thousands of scientists from across the globe was... PRICELESS! With gratitude, Milka sciencedirect.com/science/articl…


Excited to kick off our post-summer series! This Thursday we are hosting Gopal Sapkota sharing insights on redirecting phosphatase through induced proximity. **Important: The time has changed to 12 PM EST!


Congratulations to the entire Xin Zhou Lab in collaboration with the Pasi lab on this new manuscript! Thank you Xin for letting me support this incredible project. Honored and grateful to have been a part it! #SiSePuede




New studies from our lab published in CellChemicalBiology designing anti-diabetic metabolic routes using novel small molecules (SR-18292) that re-direct lactate and gluconeogenic carbon substrates to mitochondrial oxidation cell.com/cell-chemical-…

Congratulations to Dr. Thomas Roberts of Dana-Farber Cancer Biology Department for receiving the 2024 Edward J. Benz Award for Advancing the Careers of Women Faculty!

Thanks to the wonderful team at Dana-Farber Communications, Dana-Farber Chemical Biology Program Program has a new website! I am especially proud of our Careers page that includes a link to an onboarding document for incoming techs, postdocs and students! dana-farber.org/research/integ…

Xin Zhou, PhD, a researcher at Dana-Farber and her team have developed a new platform that repurposes a cancer cell's own refueling mechanism to degrade proteins driving tumor growth. This breakthrough could reshape how we approach cancer treatment. blog.dana-farber.org/insight/2024/1…

An absolute pleasure to be able to contribute to this book with the amazing Jun Qi Lab, and brilliant Qi Liu and Aimee Qi. From Royal Society of Chemistry, “Epigenetic Drug Discovery.” We specifically focus on targeting histone acetyltransferases, and new chemical strategies to target them.

Very excited for our next seminar this Thursday: Derek Bartlett (formerly Pfizer Inc., now UNC-Chapel Hill) will share insights on PK-PD modelling for TPD and Kyle Mangano (Amgen 🧪🔬🧬) will present how VIPER-TACs co-opt viral E3s. 👉Join us at 12 PM EST/ 6 pm CET (back to original schedule)!


Transferrin receptor 1 is a cell receptor that pulls iron into the cell. ♻️ The Xin Zhou Lab at Dana-Farber has investigated repurposing this receptor as a protein degradation mechanism for a potential #CancerTherapy. 📃 nature go.nature.com/4fcwd19 📰 bit.ly/4ffMGBK


🎙️ The Target 2035 podcast series is officially LIVE! In our pilot episode, meet our hosts - Milka Kostić, PhD, Rachel Harding and Opher Gileadi who share their personal motivations for joining the Target 2035 initiative. Tune in to the pilot episode now! podcasters.spotify.com/pod/show/targe… 🎧