💡🫀ICOT Clinical case of the week🫀🧠 💡 🫀Cardiomiopatia infiammatoria cronica: dalla presentazione clinica all’interpretazione della risonanza magnetica e della biopsia cardiaca 🫀 👉🔎👉🔎👉🔎👉buff.ly/3PHP7mK

💡🫀 ICOT Paper of the week 💡 A state-of-the-art review: cerebral embolic protection during transcatheter heart interventions 🫀 💡eurointervention.pcronline.com/article/cerebr… #tavi #embolicprotection #stroke #cardiology #sic #icot #cathlab

Successful first TAVI with the Medtronic Evolut FX at Federico II Cath-lab in Naples. Experiencing the beneficial impact of device innovation on procedural outcomes. Thanks to all the team and to the boss Giovanni Esposito for always aiming high for the benefit of our patients

Acute Heart Failure is an umbrella definition including multiple causes, different clinical presentations and variable prognosis. What are the data about Non-Ischemic Cardiomyopathies? Look at our comprehensive and critical review mdpi.com/2075-4418/15/5…

Proud to contribute to this fantastic issue with the main results of the POMPEII prospective study on cangrelor in patients with ACS or CCS Giovanni Esposito Marco Valgimigli Plinio Cirillo Raffaele Piccolo Anna Franzone Luigi Di Serafino Domenico Simone Castiello Lilli Manzi Mario Enrico Canonico Marisa Avvedimento

I think I have a positive bias toward the PARTHENOPE trial, not only because I was part of the Steering Committee and deeply respect the work behind it, but also because it does something rarely done when validating risk scores: randomization. Usually, we see validation based on

🚨 New issue out today! Highlights: ✅ State-of-the-Art: Antithrombotic therapy in complex PCI ✅ TAVI & redo-TAVI insights ✅ Left main CAD original research ✅ Calcium mapping with 3DStent and more Read here 👉eurointervention.pcronline.com/issue/volume-2… #CardioTwitter

In this state-of-the-art review, the authors summarize current antithrombotic strategies for patients undergoing complex PCI and discuss evidence from randomized clinical trials evaluating these regimens in this context. eurointervention.pcronline.com/article/antith…

📢 Hot off the press in the latest issue of EuroIntervention ! I am truly delighted to share the publication of our state-of-the-art review: “Antithrombotic therapy in complex percutaneous coronary intervention” 🔗Read here: eurointervention.pcronline.com/article/antith… Raffaele Piccolo Prof. Ciro Indolfi

NEW in EuroIntervention: a State-of-the-Art review on #antithrombotictherapy in complex #PCI. Balancing ischemic protection with bleeding risk remains one of the greatest challenges in this setting. This paper discusses periprocedural and long-term management strategies,

📚 ICOT CONSIGLIA 🩺 A State-of-the-Art review 🫀🔍 Antithrombotic therapy in complex percutaneous coronary intervention 📍EuroIntervention, 2025, Domenico Simone Castiello et al. 🔗 Leggi il paper completo qui: eurointervention.pcronline.com/article/antith…

The idea of low-dose intracoronary fibrinolysis is fascinating, but the STRIVE trial showed no improvement in reperfusion with low-dose alteplase in STEMI patients undergoing pPCI with large thrombus burden. Elegant study, unfortunate results, unlike what we are starting to see

The PARTHENOPE Trial, which evaluated an individualized strategy of post-PCI antiplatelet therapy using the DAPT Score compared with standard of care, broke new ground on a number of fronts. David J. Cohen, MD, MSc, Eric Secemsky MD MSc and I wrote about it in JACC Journals. jacc.org/doi/10.1016/j.…

The PROCTOR trial shakes the foundation with SVG PCI outperforming native vessel PCI: 1-year MACE 19% vs. 34%. This finding challenges decades of “native is best” dogma. Time to ask: Do we need to rewrite guidelines? #TCT2025 #JACC #CABG #PCI

“Moderate” is not benign and “severe” may demand earlier reconsideration in aortic stenosis scenario. Are we still too comfortable in the waiting room while the disease is working? #VHD #AS #AorticInterventionTiming

After CORMICA trial comfirmed the benefit of tailored, stratified therapy, the PROMISE trial shows consistent results in MINOCA. In-depth diagnosis re-classified significantly the diagnosis of epicardial spasm (13.3% -> 35.6%). A strickling reminder: Ach test is not negligible.

-Drug-coated balloons for coronary bifurcation lesions -SimoneFezzi et al. explore the role of #DCB as a stent-sparing strategy in bifurcation #PCI, highlighting procedural optimisation, hybrid approaches, and future research needs. eurointervention.pcronline.com/article/drug-c… Tuomas Rissanen

📢Prosegue la Rubrica dei Casi Clinici dalle Scuole di Specializzazione Italiane 📍Università della Calabria - Cosenza 📌Erosione di Placca in un Giovane Paziente con STEMI: una Scelta Difficile Alberto Polimeni Domenico Simone Castiello 📖 Leggi il caso completo sul nostro sito!

Validation of IVUS-defined optimal stent expansion criteria for favorable 1-year clinical outcomes 🔗pcronline.com/PCR-Publicatio… This individual patient data analysis 🔎 of the 3 largest RCTs evaluating IVUS-guided stent optimisation showed that an MSA > 5.5 mm2 was associated

#DAPT after valve-in-valve #TAVR may be associated with a lower 1-yr incidence of stroke. In contrast, no significant difference was observed for other major ischemic and bleeding outcomes or for premature valve deterioration. jacc.org/doi/10.1016/j.… #JACCINT Francesco Saia