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Excited to share the results of a huge collaborative effort Broad Institute @brighamWomens providing comparative cellular taxonomies of human and mouse adult kidneys using #scRNAseq . We studied the healthy, obese & diabetic kidney to ID shared cell states across species 1/

#NoHostageLeftBehind

A wonderful chance to work on cutting edge technologies in an inspiring environment with the nicest boss!

Beautiful new method to catch rare cell populations! Can’t wait to use it! Congrats Caleb Lareau @ChaligneRonan tsion abay

I've been eagerly awaiting this paper! The revolutionary IDH inhibitor treatment for glioma is still quite new, unexplored, and understandably met with skepticism. This incredible piece breaks down the changes in oligodendroglioma composition after treatment.

Beautiful thread discussing the similarities and differences of leading single cell analysis packages, Seurat and Scanpy. A must read for sc users, and also a wonderful example for productive respectful scientific discussion!

Celebrating completing the computational 💻 and wetlab 🧪 setups and starting our first clinical trial samples💉, along with wonderful successful rotations 🎓! 🥳🥂 P.S. Ah, yeah, I'm also 8 months pregnant 🙃

Arrived too early for a meeting and found myself sitting in the lobby, immersed in this beautiful paper about tumor heterogeneity and sc spatial organization. Highly recommended read! P.S. don't be me, keep track of time and don't miss the meeting you arrived extra early for..

What a cool and simple to use quality filter for single cell RNA! We can’t wait to try it on our data

Had a great time presenting at the tumor biology mini-symposium! What a wonderful way to bring together different labs with a common interest! Thank you Penn Medicine - Abramson Cancer Center Shelley Berger, Matthew Weitzman and Bob Vonderheide

Beautiful work! Using single-cell analysis to characterize kidney diseases, authors suggest that TREM2high macrophages may offer therapeutic benefits for diabetic kidney disease. I am delighted to see this important discovery & spotlight on therapeutics for kidney diseases!

I started my academic path in a world that already had cancer genome’s sequencing so it’s easy to forget what an incredible accomplishment it was/is! A min ago I read Penn’s report on a breakthrough for lung cancer therapy that completely relies on patient’s tumor sequencing🔬🩺

Tyler's work has consistently been innovative and reproducible, significantly advancing the field! I am excited to see all the wonderful science that the Miller lab will create 🍾🎉 👏🏽

Spent 3 hours on Friday ensuring the delivery company would pick up my old -80 freezer when they drop off the new one, following good advice to avoid future pick-up charges. Tonight, 3am, while feeding the baby, I suddenly realized we don't own an old -80... academia tired mama🙂

Combining chromatin and transcriptional profiling reveals regulatory programs driving Th17 heterogeneity and insights into CD4 T cell plasticity. Excited to share this collaboration with Alexandra Schnell out in Nature Immunology nature.com/articles/s4159…

What a fun read!

We're excited to have our own DrORourke and Zev Binder, MD, PhD presenting at next week's #Neurosurgery Grand Rounds!

In the past year, we've discovered who our friends are. In the past year, we've discovered those who excuse or even praise the massacre of Jews. In the past year, we've discovered those who stay silent when silence is not an option. In the past year, we've discovered more than