Excited to share our work on ASXL1 mutations in clonal hematopoiesis and myeloid malignancies, out in Blood Cancer Discovery Blood Cancer Discovery doi.org/10.1158/2643-3…

Wonderful to have our paper 'Deciphering cell states and genealogies of human haematopoiesis' led by Chen Weng, in a great collaboration with Jonathan Weissman's Lab, published today in nature: nature.com/articles/s4158…

The first prime editing clinical trial has been cleared by U.S. FDA to begin: prime editing of HSCs to treat chronic granulomatous disease (CGD). Congratulations to Prime Medicine on achieving this key milestone only 4.5 years after we published the first prime editing paper.

Out in Cell today! We describe the first humans with inherited, complete FLT3L deficiency. Despite a lack of most dendritic cells, they reached adulthood. See the thread below for the main highlights of our paper. cell.com/cell/fulltext/…

Mutant HSCs in human clonal haematopoiesis have an attenuated response to inflammation and ageing, which may give them a selective advantage.   Happy to share our new paper published in Cell Stem Cell: doi.org/10.1016/j.stem…   A thread below… /1

Droplet Hi-C enables scalable, single-cell profiling of chromatin architecture in heterogeneous tissues go.nature.com/3NCqwO1

Pleased to share our story Nature Communications on the discovery of genes regulating #hPSC pluripotent identity versus cell fitness through genome-scale CRISPR-Cas9 KO screens, as part of the #MorPhiC initiative aiming at establishing the function of human genes. rdcu.be/dXi72

Thrilled to announce our recent work, "Selenoprotein-Mediated Redox Regulation Shapes the Cell Fate of HSCs and Mature Lineages" @bloodjournal x.gd/NaLTC

We are excited to share our recent publication in @BloodJournal Selenoprotein-mediated redox regulation shapes the cell fate of HSCs and mature lineages sciencedirect.com/science/articl…

Incredibly insightful comments/feedback to our Blood paper from Pooranee K. Morgan and Andrew J. Murphy. "Make hematopoiesis great again: countering oxidative stress!" ashpublications.org/blood/article/… Truly grateful to all involved in this work. We will keep on deepening our science!

Happy to see that another our paper is out iScience journal cell.com/action/showPdf… Exciting insights on the chromatin remodeling factor BRD9! It exhibits distinct behaviors in fetal development compared to hematopoiesis.