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Our #ArticleinPress for today raises a question from Uni Duisburg-Essen @unidue.bsky.social, Low-Level Tragus Stimulation as a treatment for primary hypertension - a systemic reaction with a broader cardioprotective potential? (Umut Paket): ow.ly/waBT50V0ump #VagusNerve #Hypertension

Real-world findings align with clinical trial data in showing rapid weight loss with GLP-1 RAs, coinciding with increases in #RestingHeartRate mediated by changes in autonomic function. Physical activity may help offset RHR increases. ow.ly/wov250V4w6C

Finally took a look at this new aspartame paper making headlines 1) Dose - have seen folks quoting diet coke can-equivalents all over the place, from 5-50+ cans. The 0.15% dose level is ~eleven 12oz cans of diet coke when you correct for body surface area differences in mice va

dyk that women were excluded from clinical trials until the ‘90s 🤯. This had huge consequences for women’s health. The NIH Sex as a Biological Variable policy was meant to ensure female inclusion in studies & now it appears it’s being quietly dismantled. thetransmitter.org/policy/exclusi…

1.9 billion people are projected to be living with obesity by 2035, including a doubling of childhood obesity from 2020 levels by 2035. On #WorldObesityDay, the latest Editorial from The Lancet Public Health looks at how we can tackle the obesity crisis by addressing obesogenic

A new look at brain dopamine responses to ultra-processed milkshakes. Highly variable and not significantly related to adiposity in humans #obesity Kevin Hall Cell Metabolism NIH cell.com/cell-metabolis…?

Despite guideline recommendations, Lp(a) testing remains underutilized in the U.S, highlighting the need for increased awareness & adherence to screening to improve cardiovascular risk assessment @clevelandclinic ahajournals.org/doi/full/10.11…

María Torres-López (IBiS Facultad de Medicina de Sevilla) et al. examined the role of ATP in intracellular signalling in arterial #chemoreceptors during acute hypoxia and glucose deprivation 🫀 🔬 📜 Read it here: buff.ly/PGOD9ww

Inspired by Daniel J Drucker and others. Cc Team Novo Nordisk

Do you love teaching? Physics laureate Kip Thorne said “Mentoring has been one of my greatest joys,” while Carl Wieman loves learning how to pass on knowledge more effectively. #NobelPrize

Three out of four U.S. scientists are considering leaving the country. America is on the verge of a brain drain - one that will cost lives, discoveries, and our global edge.

My latest post dives into how artificial intelligence is transforming physiology and medicine—think smarter diagnostics & personalized care. #AI #Physiology #Health

If you are a scientist or engineer and want to help Congress shape AI policy over the next year - S&TPolicyFellowships is seeking applications with a May 1 deadline. Fellows will be extraordinary assets in helping Congress understand political, social, cyber and economic impacts of AI.

How does anti-tick immunity work? Scientists create a rapid antigen monitoring platform (IscREAM) and profile immune responses to #Iscapularis #tick cement proteins in humans, providing a resource for future anti-tick vaccines. Thomas Hart Molecular Microbiology and Immunology at JHSPH scim.ag/4l8u9uO

After 21 years at my dream job, I’m very sad to announce my early retirement from the National Institutes of Health. My life’s work has been to scientifically study how our food environment affects what we eat, and how what we eat affects our physiology. Lately, I’ve focused on

Ever wondered what it takes to bring a life-changing drug to market? My latest blog post, "A Billion-Dollar Gamble: How Drugs Are Developed," dives into the high-stakes world of pharmaceutical innovation. American Physiological Society #DrugDevelopment #Pharma ispyphysiology.com/2025/04/23/a-b…

The expanding universe of GLP-1 medicines-with dozens of new molecular entities in the clinic, how will they differentiate beyond #weightloss #obesity #diabetes #heartdiseasen Nature Reviews Drug Discovery nature.com/articles/s4157…

For readers interested in targeting GPCRs such as GLP-1R, this review in the April issue discusses how functional dynamics studies are revealing new routes to identify drug candidates with tailored selectivity and efficacy profiles tinyurl.com/muj99nt6 rdcu.be/ejRO8

This week on the #ISpyPhysiology blog, APS member and #APS2025 blogger Macy Stahl writes about a Summit game-changer session that discussed the benefits of #GLP1 drugs for more than just weight loss: ow.ly/B3z150VSO4N

Red blood cells drive endothelial dysfunction in #diabetes! Read our article in Journal of Clinical Investigation where we discuss the recent findings from the #PernowLab: jci.org/articles/view/… CTEC - Zurich University Heart Center #SarahCostantino Shafeeq mohammed Era Gorica