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Anyone who has ever tried to get rid of a few extra kilos knows the frustration: the weight drops initially, only to be back within a matter of weeks – the yo-yo effect has struck. Researchers at ETH Zurich have now shown that this is down to epigenetics. ethz.ch/en/news-and-ev…

Forschende der ETH Zürich haben einen Mechanismus hinter dem Jo-Jo-Effekt entdeckt: Fettzellen haben ein Gedächtnis, das auf Epigenetik beruht. ethz.ch/de/news-und-ve…

Adipose tissue retains an epigenetic memory of #obesity after weight loss nature nature.com/articles/s4158…

Even after drastic weight loss, the body’s fat cells carry the ‘memory’ of obesity go.nature.com/3YRR9nr

Fresh off the press! My paper from my PhD is finally out in nature. We discover an epigenetic memory in adipocytes of obesity that persists post weight loss. vonmeyennlab Adhideb Ghosh

New in nature🧬: We discovered why keeping weight off is so challenging - fat cells retain an epigenetic #memory of their previous state, even after weight loss. This helps explain the biology behind weight regain. Excited to share our newest work! nature.com/articles/s4158…

Great collaborative work with Laura Hinte and Daniel Castellano from vonmeyennlab is out now!

Congrats to Laura Hinte + Daniel Castellano from the vonmeyennlab for their publication in Nature! We are proud to have contributed to the #sequencing effort. Special shout-out also to our bioinformaticians who were directly involved with this work, Adhideb Ghosh and Falko J. Noé

🔵 En el mes de octubre la revista Nature publicó un artículo de nuestro investigador Daniel Castellano. Titulado "Adipose tissue retains an epigenetic memory of obesity after weight loss", aporta un entendimiento revolucionario sobre la obesidad y sus desafíos asociados.

Our newest release!🗞️ Laura Hinte, Adhideb Ghosh and Daniel Castellano created an #epigenome atlas of five histone marks from mouse brown, beige and white adipocytes during cold exposure and thermoneutrality. 🧬sciencedirect.com/science/articl…